补肾养血法治疗肾精亏虚型黄体功能不全性不孕症的临床视察.pdfVIP

提 要 目的：观察补肾养血为主的滋肾养血汤与益肾种玉汤序贯治疗肾精亏虚型黄体功 能不全性不孕症的疗效，并探讨其疗效机理。方法:将40例LPD性不孕患者随机分为 治疗组和对照组 2 组，治疗组 20 例,序贯服用滋肾养血汤与益肾种玉汤；对照组 20 例,序贯服用六味地黄软胶囊与佳蓉片，观察两组患者的临床症状、疗效、基础体温、 女性内分泌(T，P，E2 ,LH，FSH，PRL)、卵泡发育等的改善情况并进行比较。结果:(1) 治疗后两组患者的症状均较治疗前有显著性改善(P0.05)。(2)两组疗效比较有显著 性差异(P0.05)。(3)治疗组治疗后在 BBT 类型等指标上有显著改善，对照组则无显 著性改善。治疗后组间比较有显著性差异(P0.05)。(4)治疗后两组在E2，LH水平上 较治疗前均无显著性差异(P0.05)；治疗后两组 T，PRL 水平均有显著性下降 (P0.05)，FSH，P 水平显著升高(P0.05)，且两组间治疗后 PRL，FSH，P 比较亦有 显著性差异(P0.05)。(5) 能够有效刺激不良卵泡的生长发育，治疗前后排卵前优势 卵泡最大直径相比较有显著性差异(P0.01)，疗效两组无显著性差异对照组 (P0.05)。结论：LPD是下丘脑-垂体-卵巢- 子宫轴各个环节不同程度的失调导致的 一种综合征，临床上多表现为肾精亏虚症状，补肾养血为主滋肾养血汤与益肾种玉汤 治以补肾填精，养血活血为主，可从整体上调节 HPOA 轴，使其恢复平衡，从而达到 治疗LPD的目的，其临床疗效明显优于对照组。 关键词 黄体功能不全；不孕症；补肾养血法；肾精亏虚；临床观察 Clinical Observation of Bu Shen Yang Xue Treatment in Treating Inferility of essence deficiency type Luteal Phase Defect Sepeciality: Gynecology of Traditional Chinese Medicine the Study of Female Sterility. Graduate:Tan weiwei Tutor:Ye Qing Abstract Objective：To probe the reasons of LPD causing infertility furtherly, to evaluate the efficiency and to study the principle of Zishen Yangxue decoction and Yishen Zhongyu decoction tonifying kidney and invigorating vital energy,and to explore the mechanism of its efficacy.Methods ：40 cases of infertility in patients with LPD were randomly divided into treatment group and control group 2 group, 20 cases of treatment group, sequential use of ZishenYangxue decoction and Yishen Zhongyu decoction; 20 cases of the control group, taking sequential Liuwei Dihuang soft capsules and Jiarong films , the two groups were observed in patients with clinical symptoms, the efficacy of basal body temperature, for female serum hormone such as luteinizing hormone(LH), folicles timulating hormone (