补肾固冲汤治疗肾虚血瘀型青春期无排卵性功血止血疗效的临床探究.pdfVIP

提 要 目的：观察补肾固冲汤治疗肾虚血瘀型青春期无排卵性功血出血期的疗效并探讨 其作用机理。方法：将 60 例肾虚血瘀型青春期无排卵性功血患者随机分为两组：治 疗组30例，口服补肾固冲汤，对照组30例，口服益宫宁血口服液，观察两组病例近 期止血疗效，治疗前后症状及体征的改善情况，并分别测定血小板体积分布幅度、平 均血小板体积、凝血酶原时间等检测指标的变化。结果：治疗组近期止血疗效总有效 率为 93.33%，对照组的总有效率 66.67%，两组相比差异有非常显著性（P0.01）, 中医证候总有效率比较差异有显著性（P0.05），两组治疗后各项指标比较差异有显 著性（P0.05，P0.01）。结论：补肾固冲汤对于肾虚血瘀型青春期无排卵性功血出 血期具有良好的止血作用，其止血作用是通过促进凝血、调节前列腺素比例及血流变 学多个环节的作用实现的，是治疗肾虚血瘀型青春无排卵性功血出血期的有效方药。 关键词 青春期无排卵性功血；肾虚血瘀；补肾固冲汤；临床观察 Clinical Study on Hemostasis Effect of Bushen Guchong Decoction in Treating Adolescent Dysfunctional Uterine Bleeding With Kidney Deficiency and Blood Stasis Syndrome Speciality:Gynecology of TCM Tutor: Professor Wu Xinhua Author:Wang Zhuoya Abstract Objective:To observe the effect of Bushen Guchong Decoction (BSGCD) in treating hemorrhage period of adolescent dysfunctional uterine bleeding with kidney deficiency and blood stasis syndrome and to explore its mechanism. Methods :60 patients were divided into two groups at random ：the treatment group( 30 cases, treated with BSGCD) and the control group(30 cases, treated with Yigong Ningxue Mixtures). Before and after treatment, observe the changes of the hemostasis effect,the improvements of clinical symptoms,the blood rheology, latelet volume distribution amplitude (PDW) and mean platelet volune etc. Results: The totle effective rate of the treatment group was 93.33%, while that of the control group was 66.67%.There is significant difference between them （P0.01 ）. The total sign and symptom of the test group and the control group is obvious difference(P0.05). There is significant difference between the test group and the control group after treatment(P0.05，P0.01). Conclusion: BSGCD is an ef