神经元特异性烯醇化酶和抗核抗体在神经系统副肿瘤综合征诊断中的 .pdfVIP

2008 2 25 1 # 17# : 1003-2754( 2008) 01-0017-03 陈健华, 陈 琳, 崔丽英, 郭玉璞, 李晓光, 刘秀琴, 王建明 : ( NSE) (ANA) ( ESR)C ( CRP) 45, 45 NSE, ANA H ep-2, 1B 80 ESR CRP V ? s45, 9 NSE ( 20. 5% ), 45, 27 ANA( 61. 4% ) , 1B 64029 14 ( 48. 3% ) ANA , 1B 320ANA 1B 40 ESRCRP , NSE , ANA, , : ; ; ; C; : R747. 9 : A Significance of neuron-specific enolase and antinuclear antibody in the diagnosis of Paraneoplastic neurologic syn- drome CHEN Jian-hua, CHEN Lin, CUI Li-ying, et a.l (Department of N eurology, Peking Union edical CollegeHosp i- tal, ChineseAcademy of edicalSciences, Beij ing 100730, China) Abstract: Objective To i entify the sign ificance of neuron-specific enolase ( NSE ) an antinuclear antibo y (ANA) , erythrocyte se mi entation rate( ESR) , C-reactive protein( CRP) in the iagnosis of Paraneoplastic neurologic syn- rom e. M ethods There w ere forty-five sera from the patients of Paraneop lastic neurologic syn rom e an other neurologic system iseases as controls respectively. NSE w as etecte by them ean of ra iomi munity, ANA was etecte by in irect mi - munofluorenscence, ESR was etecte by photo-electric scanning, an CRPw as etecte by turb i mi etric mi munoassay. Re- sults Therew ere nine patients in the Paraneoplastic neurologic syn rom e group whose NSE were elevate . A ll of these patients ha small cell lung cancer. There were wt en ty-seven patients in the Paraneop lastic neu rologic syn rom e groups whose ANA were positive. Them ean titer