1996 ) 2005 年我院儿童细菌性痢疾的临床流行病学 - 中国感染与化疗 .pdf

2007 4 20 7 2 Chin J Infect Chemother, Apr1 2007, Vol1 7, No1 2 113 # # 1996) 2005 叶颖子, 王晓红, 王岱明 : 10 ( ) 199 6- 2 00 5 2 541 ( 323 ) , 10 , 6 - 11 1~ 6 32 3 , 8 8 . 24 % , 4. 64 % , 7 . 12% , , 2 00 0 , 10 , -, , , , : ; ; : R5 16 . 4 : B : 100 9-7 70 8( 2 00 7) 02-01 13-03 Clinical epidemiologyof Shigellosis in childrenfrom 1996to2005 YE Ying-z i, WAN G X iao-hong , WA N G Dai-ming . (Dep artment of I nf ectious Diseases, Chil rens H osp ital, Fu an University, S hanghai 2 00032, China) Abstract: Objective To investi ate the clinical epidemiolo y of Shi ellosis in children durin recent 10 years. ethodsA retrospective analysis was conducted in 2 541 children patient with Shi ellosis from 199 6 to 2 005 . Ch-i square test was used for statistical analysis. ResultsThere were sporadic cases of children Shi ellosis in Shan hai area. Most cases occurred in summer and autumn ( from June to November) . The prevalence w as hi her in children of 1- 6 years old. The clinical features of most cases belon ed to common type ( 88 . 24 %) , followed by mild type ( 4 . 64% ) and tox ic type ( 7. 12 %) . The result of bacterial typin revealed that S. f lex neri was the primary epidemic patho en, followed by S. sonnei. The prevalence of S. sonnei has risen since 20 00. In recent 10 years, the resistance of Shigella to ceftriaxone and ampicillin + sulbactam has increased. The resistance to chloramphenicol and SMZ-T MP has decreased. Conclusions Shi ellosis in children is mainly sporadic in Shan hai area. The resistance of Shigella to the third eneration cephalosporins has risen. We should use the effective antibiotics and avoid antibiotic misuse. Keywords: Shi ellosis; Children; Epidemiolo y