银翘散抗流感病毒有效部位群中的黄酮二糖苷.PDFVIP

·676· 　Chinese Traditional and Herbal Drugs　 34 8 2003 8 ·· 1 2 2 2 1 石　钺 ,石任兵 ,刘　斌 ,陆蕴如 ,杜力军 ( 1. ,　 100084;　2. ,　 100029) 　: 　。　, 。　 4,-2′-O- ( →1 2) -(Ⅰ )、-4′- -( →1 2) -(Ⅱ )、-4- -( →1 2) -(Ⅲ )、 O O -4′-O-( 1→ 2) -(Ⅳ )。 　-2′-O-( →1 2) -。 : ;;-2′- -(→1 2) - O : R284. 1　　　: A　　　: 0253 2670(2003) 08 0676 03 Studies on flavonoid glycosides with antiviral effect from Yinqiaosan on influenza virus 1 2 2 2 1 , - , , - , - SHI Yue SHI Ren bing LIU in LU Yun ru Du Li jun ( 1. School of Life Science, Tsinghua University, eijing 100084, China; 2. School of Chinese Materia Medica, eijing University of TCM , eijing 100029, China) : 　 Abstract Object To study the chemical constituents with the antiviral effect from Yinqiaosan on in- . 　 fluenza virus Methods Isolation of the constituents by different kinds of column chromatography and elucidation of their structures on the basis of chemical and spectral methods. Results　Four flavonoid gly- cosides were isolated and elucidated as 2′-O-[β-D -apiofuranosyl ( 1→ 2)-β-D -glucopyranosyl] isoliquirit- , 4′- -[ - - ( 1→ 2) - - - ] , 4- -[ - - igenin O β D apiofuranosyl β D glucopyranosyl isoliquiritigenin O β D apiofuranosyl ( →1 2) -β-D -glucopyranosyl ] isoliquiritigenin and 4′-O-[β-D-apiofuranosyl ( 1→ 2)-β-D -glucopyranosyl ] liquiritigenin, respectively. Conclusion　2′-O-[β-D-apiofuranosyl ( →1 2) -β-D-glucopyranosyl] isoliquirit- igenin is a new natu