吸水链霉菌抗金黄色葡萄球菌代谢产物-应用与环境生物学报.PDF

2010 16 2 ): 261~263 2010-04-25 应用与环境生物学报 ， ( Chin J Appl Environ Biol=ISSN 1006-687X DOI: 10.3724/SP.J.1145.2010.00261 Secondary Metabolites with Anti-Staphylococcus aureus Activity from Streptomyces hygroscopicus* 1 2 1 1 1** GONG Yumei , CHEN Jun , YANG Tao , LI Zongzhen LI Guoyou 1 ( Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China) 2 ( Pharmaceutical Institute of Chengdu Di’ao Group, Chengdu 610041, China) Abstract By monitoring and studying the antibacterial activity ofBy monitoring and studying the antibacterial activity of Streptomyces hygroscopicus 1.358 against Staphylococcus aureus, three compounds (1~3) were isolated from the ethyl acetate extract of the broth culture of S. hygroscopicus, and They were determined as RK 955A (1), nigericin (2) and elaiophylin (3) on the basis of spectroscopic data. Compounds 1~3 showed significant antibacterial activities against S. aureus. Fig 1, Tab 1, Ref 18 Keywords Staphylococcus aureus; Streptomyces hygroscopicus; nigericin; elaiophylin; secondary metabolite; antibacterial activity CLC Q936 吸水链霉菌抗金黄色葡萄球菌代谢产物* 1 2 1 1 1** 龚雨梅 陈 军 杨 涛 李宗珍 李国友