临床合理用药系列讲座(5)（Clinical medicine series lecture series (5)）.doc

临床合理用药系列讲座(5)（Clinical medicine series lecture series (5)） Clinical medicine series lecture series (5) Research progress of cough medicine and its clinical application 100017 Beijing peoples liberation army 305 hospital gong lian hongli Keywords: drug research progress; Rational drug use; Chinese book classification no. : R 972 + 14 1. Progress in drug research The central - dependent cough medicine mainly refers to morphine alkaloid And its derivative, has the very obvious effect of the town cough. Because of that Objects are dependent, so they are only briefly used when other treatments are ineffective. Commonly used drug is codeine, the drug directly inhibits the central area of the brain, the town coughs It is strong and fast, and also has analgesic and sedative effects. For various reasons Severe dry cough and irritating cough, especially with chest pain Cough. But codeine can inhibit the secretion of the bronchial gland and can make sputum sticky Thick, hard to cough out, so it is not suitable for patients with mucus. Oral or skin The injections were administered from 15 to 30 mg each time, 30 ~ 90 mg per day. Major adverse The response is dizziness, lack of concentration, nausea, vomiting, constipation, abdominal pain, snoring It is weak, slow or irregular, euphoric and fidgety. redosing Develop resistance, long use of dependence. Falkine and codeine Similar, used for severe dry cough, but less dependent. Oral 5 ~ 10 mg. Adverse reactions with morphine, nausea and lethargy. There are many antitussive agents in central Africa. In the current The most widely used on the bed is dextrin, which is similar to codeine, but no Analgesic and hypnotic effect, the therapeutic dose has no inhibitory effect on the respiratory center Dependencies. All kinds of non-prescription compound cough medicine contain this medicine. Used in the sense of Risk, acute or chronic bronchitis, bronchial asthma, pharyngitis, tuberculosis And other upper respiratory tract infection caused b