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生物总结(Biological summary)
The first DNA is the main genetic material
1. Transformation of pneumococcus pneumoniae
(1) transformation of the body: in 1928, by the British scientist Griffith et al.
Conclusion: there is a conversion factor in s-type bacteria, which can transform r-type bacteria into s-type bacteria.
(2) in vitro transformation experiment: in 1944, by American scientist Avery et al. Conclusion DNA is a genetic material
2. Experiments on bacteriophage infection of bacteria. Conclusion: DNA is a genetic material
The vast majority of organisms (cellular structures and DNA viruses) have the genetic material of DNA, so DNA is the main genetic material.
Section 2 structure of DNA molecules
The structure of a DNA molecule
1. Chemical structure: deoxyribonucleotide is connected to the deoxynucleotide chain. Phosphorus and sugar are skeletons, bases.
2. Spatial structure: double helix of rules (double stranded spiral structure, opposite polarity)
3. Structural features: the stability: the lateral is the phosphoric acid and deoxyribose connection, the base a-t, c-g pairing.
Diversity: base pairs vary in sequence, hundreds of thousands. Specificity: each species has a specific base arrangement.
2. Related calculation
(1) A = T C = G
(2) (A + C)/(T + G) = 1 or A + G/T + C = 1
(3) if (A1 + C1)/(T1 + G1) = b then (A2 + C2)/(T2 + G2) = 1 / b
(4) (A + T)/(C + G) = (A1 + T1)/(C1 + G1) = (A2 + T2)/(C2 + G2) = A
3. Determine the type of nucleic acid
(1) if there is no T, then this nucleic acid is RNA; (2) if there is T and A = T C = G, then double stranded DNA;
(3) if there is T and A does not equal T C, then it is single stranded DNA; (4) both U and T are in the transcription stage.
Section 3. DNA replication
Experimental evidence of DNA semi-retained replication. Conclusion: DNA molecule replication is semi-retained.
The process of DNA replication
1. Time: intersecessionist and meiotic interphase
2. Conditions: template - DNA double strand raw materials - four free deoxy
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