氩离子激光激发自体荧光诊断人体表恶性肿瘤的研究pdf.PDFVIP

1 4 3 4　　　　　　Ch inese J LaserM ed Surg 3(4) ∶203～ 20 ( 1 4)　 氩离子激光激发自体荧光诊断人体表 恶性肿瘤的研究 1 1 2 曾超英　杨　栋　曹庆清 D iag nos is of Body Surface T umo rs by A rgon La ser Induced A utof luo rescence Spect ra A na lys is Zeng C haoy ing　Yang Dong　C ao Q ingq ing Cancer R esearch C en ter, X iam en U n iv ers iyt , X iam en ( 361005) 　, (OM AⅢ ) 。 , , , , 。 203、 600, : 86% ( 60/70), 、 7% ( 2 /30), 14( 103) 600、。 、 , 2。 , 2mm 。 。 　　　　 AB STRACT C haracteristics of laser indu ced au tof luorescence spectra o f tum ors have been studied clinically w ith a de- tecting system w h ich consists of an argon laser and an opticalm u lt ichannel analyzer, Th rough the analy sis of endogenou s porphy rin specific peaks, 70 cases of m alignan t tum ors, 30 cases of severe dysp lasia, 103 cases of benign tum o rs of ch ron ic inflamm ation and 600 cases o f norm al tissue in oral cavity or sk in w ere diagnosed . w ithou t any fluorescen t d rug T he resu lts show ed that the pos itive rate o f m alignant tum ors and dysplastic lesions w ere 86% ( 60/70) and 7% ( 2 /30), respectively, w h ile all benign lesions in 103 cases and norm al m ucosa or sk in in 600 personsw ere negative. Tw o cancer foci sm aller than 2mm w ere detected by th is p roce- . , du re Du ring follow ing up by fluorescence analy sis for dysp last ic lesion s squam ous cell carcinom a occu rred , . in tw o cases w hose specific f luorescence w ere positive K ey w ords　A rgon laser, A utofluorescence spectrum, D iagnosis, M align