坦索罗辛治疗应用山莨菪碱后排尿困难研究.doc

坦索罗辛治疗应用山莨菪碱后排尿困难研究[摘要] 目的 探讨坦索罗辛治疗应用山莨菪碱后并发排尿困难的疗效。方法 本组23例患者给予山莨菪碱后出现排尿困难,立即给予盐酸坦索罗辛0.2mg,2例合并前列腺增生患者一次性导尿和肌注新斯的明0.5mg,其余23例患者均给予坦索罗辛0.2mg,1次/d,直到输尿管结石排净。结果 给予坦索罗辛后,21例患者自行排尿道畅,2例合并前列腺增生患者也能较好地自行排尿,无不良反应发生。结论 坦索罗辛治疗应用山莨菪碱并发排尿困难是安全、有效的。 [关键词] 坦索罗辛; 山莨菪碱; 排尿困难; 导尿术; 输尿管结石 [中图分类号] R69 [文献标识码] A [文章编号] 1673-9701(2009)23-62-02 Analyse the Treatment of Tamsulosin on Difficulty of Urination after Using Anisodamine REN Zhongzhi ZHANG Lin ZHANG Da HE Yiguang The Second People’s Hospital of Guangyuan City,Guangyuang 628017,China [Abstract] ObjectiveTo explore the effects of tamsulosin on difficulty of urination after using anisodamine. Methodspatients of 23 cases had difficulty of urination after using anisodamine. 23 cases were given tamsulosin 0.2mg immediately. 2 cases with bengin Prostatic- hyperplasia were had one?s catheterization and given intramuscular neostigmine 0.5mg. All patients were given tamsulosin 0.2mg,once a day,in coures up to ureteral stone complete discharging. ResultsPatients of 21 cases had well own voiding urine after used tamsulosin,Patiests of 2 cases with benign prostatic-hyperplasia had weller own voiding urine,no adverse reaction has been reported. ConclusionIt is demonstrated that tamsulosin are safe and effective for difficulty of urination after using anisodamine. [Key Words]Tamsulosin; Anisodamine; Difficulty of urnation; Catheterization; Ureteralstone 2005年7月～2009年1月,我们收治疗23例输尿管下段结石患者并发肾绞痛,在应用山莨菪碱静脉输液解痉时,出现排尿困难,我们使用坦索罗辛治疗,取得了较好的疗效,现报道如下。 1 资料与方法 1.1 一般资料 本组23例患者均为男性,年龄32～48岁,平均42.5岁。左侧输尿管下段结石者15例,右侧输尿管下段结石者8例,结石直径0.8～1.2cm。2例合并前列腺Ⅱ度增生。23例患者均为输尿管结石体外冲击波碎石治疗后肾绞痛发作,静脉输入山莨菪碱20mg后排尿困难,下腹部胀痛。 1.2 治疗方法 本组23例患者给予山莨菪碱后出现排尿困难,立即给予盐酸坦索罗辛0.2mg,2例合并前列腺增生患者一次性导尿和肌注新斯的明0.5mg,其后23例患者均给予坦索罗辛0.2mg,1次/d,直到输尿管结石排净。 2 结果 23例患者给予坦索罗辛后,21例患者自行排尿通畅,2例合并前列腺增生患者,一次性导尿后也能较好的自行排尿。患者下腹部胀痛消失,肾绞痛症状明显减轻,并输尿管结石排净,无其他不良反应。 3 讨论 急性肾绞痛是泌尿外科常见的急腹症之一,发病急,症状重,绝大多数患者疼痛剧烈,常合并呕吐、腹胀,输尿管下段结石还可以诱发尿频、尿急、尿痛及血尿等症状。患者容易出现情绪不稳定,如治疗不及时,特别是用