平阳霉素联合地塞米松局部注射治疗儿童眼睑海绵状血管瘤.doc

平阳霉素联合地塞米松局部注射治疗儿童眼睑海绵状血管瘤[摘要]目的：观察分析平阳霉素联合地塞米松局部注射治疗儿童眼睑海绵状血管瘤的临床效果。方法：采用平阳霉素8 mg联合地塞米松5mg，用2%利多卡因1ml，生理盐水2ml稀释成4ml，血管瘤瘤体内注射治疗58例儿童眼睑海绵状血管瘤，按每次药量及方法1周或隔周注射1次，分别为多次注射治疗，每次剂量最多不超过8mg，直致瘤体消失。结果：随访观察6～24个月, 55例患儿血管瘤全部消失达到治愈, 3例有效，未发生局部感染、组织坏死及瘢痕畸形。结论：应用平阳霉素联合地塞米松局部注射治疗儿童眼睑海绵状血管瘤，具有治愈率高、操作方便、副作用小，有效的恢复了眼睑的正常外形与功能。 [关键词]眼睑海绵状血管瘤；儿童；平阳霉素联合地塞米松 [中图分类号]R777.1 [文献标识码]A [文章编号]1008-6455（2012）01-0033-03 Pingyang DX combined with dexamethasone local injection treatment children cavernous hemangioma of the eyelid HE Ya-ni,DUAN Zhi-guang,LI Gui-xiang (Department of Ophthalmology,Dali Prefecture People’s Hospital,Dali 671000,Yunnan,China) Abstract: Objective Observation and analysis in Pingyang combined with dexamethasone local injection treatment children cavernous hemangioma of the eyelid clinical effect. Methods Used in Pingyang in 8 mg combined with dexamethasone on 5mg 1ml,with 2% lidocaine,saline diluted 2ml into 4ml, tumor with injection in the treatment of 58 cases of children cavernous hemangioma of the eyelid,according to each charge and method for a week or every other week 1 injections, respectively,repeated injection therapy, each dose not more than 8mg,until the tumor disappeared. Results They were followed up for 6 to 24 months,55 cases of children with hemangiomas disappear to cure 3 cases,effective,no local infection,tissue necrosis and scar deformity. Conclusion The application of Pingyang DX combined dexamethasone local injection for the treatment of children cavernous hemangioma of the eyelid, has a high cure rate,convenient operation,small side effect,effective in the restoration of the normal shape and function of the eyelid. Key words:cavernous hemangioma of the eyelid; children; Pingyang DX combined with dexamethasone 海绵状血管瘤是儿童先天性肿瘤或血管畸形，儿童时期的血管生长迅速，加之眼睑与颌面部组织的血供丰富，因此，位于该部位的血管瘤生长较快，若不及时治疗会产生不同程度的眼部畸形和功能障碍，尤其是上睑的海绵状血管瘤可造成上睑下垂,可引起儿童的视力障碍。笔者采用平阳霉素联合地塞米松局部注射治疗儿童眼睑海绵状血管瘤58例，经临床观察疗效显著，治愈率高、操作方便、副作用小，愈后能恢复眼睑的正常形态与功能。 1 资料和方法 1.1 一般资料：本