泌尿生殖道感染支原体鉴定及药敏研究.docVIP

泌尿生殖道感染支原体鉴定及药敏研究【摘要】目的 了解本地区解脲支原体(Uu)及人型支原体(Mh)引起的泌尿生殖道感染及其药物敏感情况，为临床治疗提供合理的抗生素依据。方法 应用支原体培养鉴定药敏试剂盒，对2917例疑为支原体感染患者的泌尿生殖道分泌物进行培养，并测定其对10种常用抗生素的敏感性。结果 支原体阳性1457例（49.95%），其中女性标本阳性率为53.86%，男性标本阳性率为28.25%，Uu、Mh、Uu+Mh检出率分别为25.54%、5.04%、19.37%。对Uu敏感率最高的抗生素是交沙霉素，耐药率最高的抗生素是环丙沙星。结论 泌尿生殖道支原体感染已相当普遍，以Uu阳性率最高，女性感染率明显高于男性，临床要根据药敏结果合理选用抗生素，降低耐药菌株的产生。 【关键词】解脲支原体（Uu） 人型支原体（Mh） 药敏分析 中图分类号：R446.5文献标识码：B文章编号：1005-0515（2011）1-326-03 Urogenital tract mycoplasma infection and drug susceptibility of identification Liao Xiang-Jian Li Song Wu Jie (Laboratory Medicine Hospital of Changsha City, Hunan, Changsha410100) 【Abstract】Objective To understand the region, Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) urogenital infection caused by their drug sensitivity for clinical treatment of antibiotics to provide a reasonable basis. Method The susceptibility of Mycoplasma culture and identification kits, and 2,917 cases of mycoplasma infection in patients with suspected urinary genital tract secretions for culture and determination of 10 kinds of commonly used antibiotics. Result 1457 cases of mycoplasma positive (49.95%), and women, the positive rate was 53.86%, men, the positive rate was 28.25%, Uu, Mh, Uu + Mh detection rates were 25.54%, 5.04%, 19.37%. Uu the highest rate of antibiotic is sensitive to josamycin, the highest rate of antibiotic resistance is ciprofloxacin. Conclusion Mycoplasma infection is quite common, to Uu-positive rate was the highest rate of female was significantly higher than men, according to susceptibility results of clinical rational use of antibiotics and reduce drug resistant strains. 【Key words】Ureaplasma urealyticum (Uu) Mycoplasma hominis (Mh) sensitivity analysis 支原体是一类无细胞壁，大小介于细菌和病毒之间，能在无生命培养基中生长繁殖的最小原核细胞型微生物。引起泌尿生殖系统感染的支原体主要有两种，即解脲支原体(Uu)和人型支原体(Mh)，其发病率较高，已越来越引起临床的关注。近年来，由于广谱抗生素的滥用，导致耐药菌株日益增多，且出现多重耐药性。为了掌握支原体感染的现状及对抗生素的耐药情况，为临床正确诊断和早期治疗疾病提供科学依据，本文对2008年6月至2010年6月2917例支原体感染的泌尿生殖道标本进行支原体培养鉴定及药敏分析，现报道如下。 1 材料和方法 1.1 标本来源