有机锡化合物的污染及其毒性-中国食品卫生杂志.PDF

[ 29] Bob B Buch anan. Genetic engineering and the allergy issue adverse reactions to celery root [ J ] . J Allergy Clin Immu [ J] . Plant Physiol, 2001, ( 126) 5 7. nol , 2000 , ( 106) 373 378. [ 30] Akiyam a H , T eshim a R, Sakushima J, et al . Exam ination of [ 32] Sorva R, MakinienKiljunen S , JuntunenBackman K. oral sensitization w ith ovalbum in in BrownNorway rats and Lactoglobulin secretion in hum an milk varies w idely after three strains of m ice[ J] . Immunol Lett , 2001, ( 78) 1 5 . cow s milk ingestion in mothers of infants w ith cow s m ilk [ 31] Ballm erWeber BK, Vieths S, Luttkopf D, et al. Celeryal allergy[ J ] . J Allergy Clin Immunol , 1994, ( 93) 787 lergy conf irm ed by doubleblind, placebocontrolled food 792. ch allenge a clinical study in 32 subj ects with a history of [ 2003- 03- 28] R15; Q3431 E 1004- 8456( 2003) 03- 0238- 07 王永芳 ( 卫生部卫生监督中心, 北京 100007) 为了解有机锡化合物污染及其毒性的研究成果, 从有机锡化合物对海洋的污染状况污染 来源有机锡化物对海洋 物以及人体健康的毒性等方面进行了综述实验证明有机锡化合物尤 其是三苯基锡和三 丁基锡, 能够引起雌性软体动物变性哺乳细胞 殖毒性以及人体免疫毒性 等有机锡化合物作为一种防污涂料被广泛应用于船体和海洋建筑等, 因此导致了海产品中残留 了大量的有机锡化合物, 这些化合物可以通过食物链影响人体健康人类食用了含有机锡化合物 的海产品后, 对人体健康可能造成的潜在危险, 其危害机理尚需进一步研究 有机锡化合物; 环境污染; 食品污染 The contaminative status of organic tin compounds and its toxicity Wang Yongfang ( National Center for Health Inspection and Supervision, China, Beijing 100007) Abstract The contaminat ive status and the sources of organic tin( organotin) compounds in marine environ ment and its toxicity to marine animal and human w ere summarized. It has been found that organotin compound can induce imposex in female gastropods, reproductive toxicity and genotoxicity on mammalian cells,