Chapter8 Gene mutation,DNA repair, and transposable elements课件.ppt

Xunchao Xiang Southwest University of Science and Technology 8.5 The molecular basis of mutation The absence of a nitrogenous base at an AP sites will alter the genetic code if the strand involved is transcribed and translated. If replication occurs, the AP site is an inadequate template and can cause replication to stall. Deamination: an amino group is converted to a keto group in cytosine and adenine. In these two cases, cytosine is converted to uracil and adenine is changed to hypoxanthine(次黄嘌呤). 俏畅陌铲氏侠燕蛀典牛浆结赠葛钵瑞昏拆胚啮羹暇认屡赐鬼滋释灯纷侄迂Chapter8 Gene mutation,DNA repair, and transposable elemen