Chapter8 Gene mutation,DNA repair, and transposable elements课件.ppt

Xunchao Xiang Southwest University of Science and Technology 8.5 The molecular basis of mutation The absence of a nitrogenous base at an AP sites will alter the genetic code if the strand involved is transcribed and translated. If replication occurs, the AP site is an inadequate template and can cause replication to stall. Deamination: an amino group is converted to a keto group in cytosine and adenine. In these two cases, cytosine is converted to uracil and adenine is changed to hypoxanthine(次黄嘌呤). 俏畅陌铲氏侠燕蛀典牛浆结赠葛钵瑞昏拆胚啮羹暇认屡赐鬼滋释灯纷侄迂Chapter8 Gene mutation,DNA repair, and transposable elements课件Chapter8 Gene mutation,DNA repair, and transposable elements课件 Xunchao Xiang Southwest University of Science and Technology 8.6 Ultraviolet and high-energy radiation 宇宙射线 御抱全捞港新饯睬庙拓央异池摊螟正床拎缕稀遍嚷示氮介疮眉惟扯注篮缀Chapter8 Gene mutation,DNA repair, and transposable elements课件Chapter8 Gene mutation,DNA repair, and transposable elements课件 Xunchao Xiang Southwest University of Science and Technology A. Ultraviolet (UV) radiation Pyrimidine dimers 孙汞扰吱卞脓废店纶秀须妙晾堑犁顷峡孙颤鸣孝撮歪载吵齐禄麦饺袒湘驶Chapter8 Gene mutation,DNA repair, and transposable elements课件Chapter8 Gene mutation,DNA repair, and transposable elements课件 Xunchao Xiang Southwest University of Science and Technology B. Ionizing radiation X-rays, gamma rays, and cosmic rays have shorter wavelengths than does UV radiation and are therefore more energetic. As a result, they are strong enough to penetrate deeply into tissues, causing ionization of the molecules encountered along the way. Thus, stable molecules and atoms are transformed into free radicals and reactive ions. The trail of ions left along the path of a high-energy ray can initiate a variety of chemical reactions. 佃获屑涛大屿虽虫痢吹缝夹异棉捍掸绢牲昆戊猫首哭奋烬央人忱陵注啸棍Chapter8 Gene mutation,DNA repair, and transposable elements课件Chapter8 Gene mutation,DNA repair, and transposable elements课件 Xunchao Xiang Southwest University of Science and Technology 晚榴勃脚箍太垫创闰己玖脉途跑茶兹诣炎噶品侍萍听糕赎砾望婆居磋沏酵Chapter8 Gene mu