洪灾区肾综合征出血热的流行病学研究.pdfVIP

中南大学学报 学版) JC 201】，36(3) bttp：／／xbyx．xysm．net 、 entSouth UnivfMedSc) … ’ J ‘，…… 一 223 Epidemiologicalstudyonhemorrhagicfeverwithrenalsyndrome inflood areas ZHOUJia，ZHANG Xiao，CHEN Mengshi，HUANGXin，LIUAizhong， YANGTubao，TANG Hongzhuan (SchoolofPublicHealth，CentralSouthUniversity，Changsha410008，China) Abstract： Objective Toinvestigatetheinfectionofhemorrhagicfeverwithrenalsyndrome (HFRS)inhostanimalsandinapparentinfectionofHFRSingeneralpopulationinDongtingLake areasafterfloods．M ethods ThenJghttrappingmethodwasusedtocapturerodents．Theimmuno— fluorescenceassayswereusedtodetectthehantavirus(HV)antigensandantibodiesinrodentslung andintheSeHlm ofgeneralpopulation．Nonconditionallogisticregressionwasappliedtoanalyzerisk factorsfnrinapparentinfectionwithHV．Results Infloodregion．draw—nearfloodregionandnew migrationregion，rodentdensitywas6．95％ ，6．28％ ，and8．67％ ，respectively，andthevirus—car— ryingrateinrodentswas15．07％ ，9．25％ ，and4．47％ ，respectively．Thevirus。carryingratindex wasthehighestinfloodregion(0．10)．Apodemusagrariuswasthedominantspecies．Thestandard． izedpositiverateofHV antibodyingeneralpopulationfrom abovementionedregionswas4．49％ ， 3．11％ ．and3．13％ ．respectively．Therewasnosignificantdifferenceamongdifferentageorgen— dergroups．Theresultsoflogisticregressionanalysisindicatedthatpeoplewhowereinvolvedincon— sturctionofwaterconservancyfacilitiesinwinterorpracticeofratextermination athomewerethe principalfactorsrelated toinapparentinfectionwithHV．Conclusion Thevirus-carryingrate in mainhostanimalsofHV inthe3regionsishigh，whereasthepositiverateofHV antibodyislow in generalpopulation．ComprehensivemeasuresshouldbetakentopreventandcontrolHFRS，suchas reinforcingsurv