包膜对猪扩张后动脉筋膜皮瓣血供影响探究.doc

包膜对猪扩张后动脉筋膜皮瓣血供影响探究[摘要]目的：探讨包膜切除与包膜保留，对猪扩张后超长动脉筋膜皮瓣血流动力学、氧代谢及皮瓣活力的影响，为临床处理皮瓣包膜提供参考。方法：9～12个月龄成年小型香猪8只，每只猪对称各设计1个以胸背动脉穿支血管为蒂、面积为5cm×20cm的扩张后动脉筋膜皮瓣。实验组扩张后动脉筋膜皮瓣包膜切除，对照组皮瓣包膜保留。比较二组皮瓣的血氧饱和度、MDA含量和成活长度的变化。结果：实验组扩张后动脉筋膜皮瓣的血氧饱和度低于对照组；MDA含量高于对照组；成活长度小于对照组。结论：包膜增加了扩张后动脉筋膜皮瓣的血供，应该予以保留。 [关键词]包膜；动脉筋膜皮瓣；血供 [中图分类号]R622 [文献标识码]A [文章编号]1008-6455（2011）02-0222-04 Study on effect of the capsular tissue on the blood supply of expanded artery-pedicled fasciocutaneous flaps in the pig ZHANG Zhi-hong1, WANG Jia-qi2, LI Wen-zhi1 (1.Department of Plastic Surgery and Laser Medcine, Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing 100029, China; 2. The Third Plastic Department of Plastic Surgery Hospital, Chinese Academy of Medical Sciences,Beijing 100041,China) Abstract:ObjectiveTo discuss the effect of capsulectomy on the hemodynamics, oxygen metabolism and viability of the expanded artery-pedicled fasciocutaneous flaps in the pig. It provides references of clinical management for the capsular tissue.Methods20 cephalicly based expanded fasciocutaneous flaps with axial-pattern blood flow, 5cm×20cm, were designed on each back skin, using piglets aged 9～12 months as an experimental model. Group C was expanded flap with capsulectomy. Group D was expanded flap with intact capsular tissue. The expanded skin flaps with capsulectomy at the time of flap elevation were in experimental group, and flaps with intact underlying capsular tissue were in control group. Compare the changes oftissue oxygen saturation, malondialdehydecontent and the length of flap viability in two groups.ResultsTissue oxygen saturation values in control group were lower than that in experimental group, the MDA content in control group was higher than that in experimental group, and the length of flap viability in control group was shorter than that in experimental group.ConclusionsThe capsular tissue adds blood supply to the expanded artery-pedicled fasciocutaneous flaps,and it should