地塞米松联合消痣灵局部注射治疗血管瘤及血管畸形疗效观察.doc

地塞米松联合消痣灵局部注射治疗血管瘤及血管畸形疗效观察[摘要]目的：观察地塞米松联合消痔灵注射治疗婴幼儿血管瘤及血管畸形的疗效。方法：收集我科2008年4月～2010年5月以地塞米松联合消痔灵注射治疗体表血管瘤、血管畸形的153例患者临床资料进行分析。结果：153例患者中，治愈116例，治愈率为75.8%，显效28例，显效率为18.2%，无效9例，无效率为6.0%。结论：地塞米松联合消痔灵局部注射治疗血管瘤及血管畸形具有疗效高、副作用少、损伤小等优点，是一种简便、安全有效的方法。 [关键词]血管瘤；血管畸形；地塞米松；消痔灵；局部注射 [中图分类号]R732.2 [文献标识码]A [文章编号]1008-6455（2011）04-0630-02 Mixed injection of Xiaozhiling with Dexamethasone in the treatment of infantile hemangioma and vascular malformation CUI Chao，ZHANG Rong-ming (1.Liaoning Medical University,Jinzhou 121000,Liaoning,China;2.Department of Plastic Surgery，Liaoning Medical University，Jinzhou121000,Liaoning,China) Abstract：0bjectiveTo explore a safe，efective and minimally invasive therapy of infantile hemangioma and vascular malformation with the combined injection of Xiaozhiling and Dexamethasone． MethodsApply the injection of Xiaozhiling with Dexamethasone interstitial tissue of the hemangioma and vascular malformation in 153 patients that admitted to our department from 2008 to 2010． ResultsThe 153 patients with infantile hemangioma and vascular malformation were treated.The cure patients were 116 cases and the cure rate was 75.8%，the efective patients were 28 cases and the efective rate was 18.2%,the inefective patients were 9 cases and the inefective rate was 6.0%．ConclusionThe injection of Xiaozhiling with Dexamethasone in treating infantile hemangioma and vascular malformation can well control the growth of the lesion．It is a safe，efective therapy with less complications． Key words：infantile hemangioma；vascular malformation；xiaozhiling；dexamethasone；injection 近年来外国学者Mulliken和Glowacki应用他们的生物学分类方法，将血管性疾病分为血管瘤和血管畸形[1]，血管瘤及血管畸形的治疗方法有多种，注射药物疗法、同位素敷贴治疗、激光治疗、冷冻疗法和手术治疗等，其中注射治疗的注射药物通常为激素、平阳霉素、硬化剂、H1受体阻滞剂、干扰素等。2008年4月～2010年5月，笔者从门诊筛选愿意接受注射治疗并配合观察随访半年以上的血管性疾病患者153例为治疗对象，应用地塞米松联合消痔灵局部注射治疗血管瘤及血管畸形，取得了较好的疗效。 1 资料和方法 1.1临床资料：患者153例，男41例，女112例。年龄1个月～16岁，其中小于1岁者87例，1～5岁54例，大于5岁者12例。本组中血管瘤78例，血管畸形49例，混合畸形26例。病变部位：头面部83例，躯干及四肢57例，会阴13例。皮损大小：0.8cm×1.0c