强脉冲光及脉冲染料激光595nm治疗面部毛细血管扩张比较探究.docVIP

强脉冲光及脉冲染料激光595nm治疗面部毛细血管扩张比较探究[摘要]目的：评价强脉冲光（Intense Pulsed Light，IPL） 560～1 200nm/590～1 200nm和脉冲染料激光595nm不同波长治疗面部毛细血管扩张症的临床有效性。方法：301例患者随机分为3组，A组(IPL560～1 200nm)124例，B组(IPL590～1 200nm)79例，C组(脉冲染料激光595nm)98例。分别治疗1～4次，间隔时间4～6周。观察其血管清除率。结果：A、B、C组术中血管完全消失分别为66例(53.23%)、34例(43.04%)、74例(75.51%)；治愈分别为79例(63.71%)、41例(51.90%)、81例(82.65%)；平均治愈次数分别为2.66次、 2.85次、1.65次。A、B、C三组总体比较差别具有统计学意义；A、B两组比较差别具有统计学意义；A、C两组和B、C两组比较差别具有统计学意义。结论：IPL560～1 200nm/590～1 200nm和脉冲染料激光595nm三种波长对面部毛细血管扩张均有可靠疗效，脉冲染料激光595nm波长治愈率优于IPL560～1 200nm/590～1 200nm波长。 [关键词]面部毛细血管扩张症；IPL；脉冲染料激光；疗效；临床研究 [中图分类号]R751 [文献标识码]A[文章编号]1008-6455（2009）02-0221-04 Comparison of intense pulsed light to 595nm pulsed dye laser for treatment of facial telangiectasia : a pilot study WANG Yong-xian,YING Zhao-xia,LIU Ping,Wang Qiong-yu,GE Wen-yu,QIAO Li (Department of Dermatology,the Second Hospitol,Xi’an Jiaotong University, Xi’an 710004,Shaanxi,China) Abstract:Objective The aim of this study is to evaluate efficacy of intense pulsed light(IPL560～1 200nm/ 590～1 200nm) and pulsed dye laser(595nm) in treatment for facial telangiectasia. Methods301 consecutive patients with facial telangiectasia were randomly divided into three groups: group A(124) were treated with IPL560～1200nm; group B(79)were treated with IPL590～1200nm; group C(98) were treated with pulsed dye laser(595nm). They were treated one and to four times with IPL or PDL. The interval was four to six weeks between two treatments. The ratio of elangiectasia disappeared was observed. ResultsThe proportion of elangiectasia disappeared entirely from group A, group B and group C were 53.23%, 43.04% and 75.51% respectively. The cure rate were 63.71%(group A), 51.90%(group B) and 82.65%(group C) respectively. The advantage number of treatment times were 2.66(group A), 2.85(group B) and 1.65(group C) respectively. There is significant difference between group A and group C, or group B and group C. There is no difference between group A and group B.ConclusionTh