仿生合成梯度含锶磷酸钙骨水泥的体外细胞生物学性能检测.pdfVIP

巾|司组织i科研究与临床康复 第 1 2 ;(ff !/41 JI!J 2008 - 01 - 01 山版 Joumal ofClinical Rehabilitati四 nssue Eng illeerillg R时earch Janllary / , 2008 Vo1.l2, No. / ~Jé，~基础实验 仿生合成梯度含锦磷酸钙骨水泥的体外细胞生物学性能检测会 岳 进1 毛天球 d; 德林吁，享11 人刚2 Biomimetic syntbesis of gradient Sr-containing calcium phosphate cement and cytobiological performance assay in vitγ。 2 Yue Jin 1, Mao Tian-qiu 1, Lei De-lin 1, Guo Da-gang Abstract AIM: This study constructcd novel gradienl Sr-containing ca lcium pho sphale ccmcnt (CPC) by means of biomimelic synthesis and Departm enl 01 investigated the biocompatibi lity ofthis materi al using L-929 日brobl asts and youn吕 rabbit osteoblasts Oral-Maxi llofacial Sur吕cry. Stol11a- METRODS: From Novcmbcr 2006 to April 2007 , Lhe experimcnt was carricd Ollt in the Department of Oral-Maxillofacial SlIrgcry吨 lological Col legc, Stomatological College at the Fourth Military Medical University of Chi nese PLA and ihe State Kcy Laboratory for Mechanica l Fourth Mllilary Behavior of Materials at Xian J削long University.( Novel gradient Sr-containing CPCs were biom imetic synthcsizcd.( The new Mcdical Unlvcrsity biorn aterial s were contacted with L-929 日broblasL cell s and rabbits osteob lasts in different situations .( MTT assay was used to 01 Chinese PLA. Xian 7t0032‘ detcct th e cell proliferation activity , and relative prol iferation rate was cal clll at巳d and graded accord ing to 6-lcvcl toxici ty Shaanxi Provínce. classification . Mo叩hology of ccll s was dete口