chemotherapy-induced oesophageal stricture in a child with osteosarcoma a case report在孩子与骨肉瘤化疗所致食管狭窄病例报告.pdfVIP

Hindawi Publishing Corporation Chemotherapy Research and Practice Volume 2010, Article ID 240763, 3 pages doi:10.1155/2010/240763 Case Report Chemotherapy-Induced Oesophageal Stricture in a Child with Osteosarcoma: A Case Report Daichi Ishimaru,1 Takatoshi Ohno,2 Masato Maeda,1 Yutaka Nishimoto,2 and Katsuji Shimizu2 1 Department of Orthopaedic Surgery, Takayama Red cross Hospital, Tenman-cho 3-11, Takayama, Gifu 506-8550, Japan 2 Department of Orthopaedic Surgery, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan Correspondence should be addressed to Daichi Ishimaru, ishimarudaichi2003@yahoo.co.jp Received 9 February 2010; Accepted 8 June 2010 Academic Editor: Paolo Pronzato Copyright © 2010 Daichi Ishimaru et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Treatment with a combination of chemotherapy and radiotherapy is known to be associated with oesophageal stricture in both children and adults with malignancies. However, oesophageal stricture resulting from chemotherapy alone is a rare complication, with few reports on it. We experienced a rare paediatric case of oesophageal stricture caused by chemotherapy for osteosarcoma of the left distal femur. After completion of the chemotherapy course, the patient showed dysphagia caused by the oesophageal stricture and underwent balloon dilatation for the oesophageal stricture. After balloon dilatation, he was able to ingest solid foods, and the oesophagus was normal without any strictures at the last follow-up (20 months after ballooning). Therefore, oesophageal stricture should be considered as a complication