原创力文档biocompatibility of nanoporous coating on niti alloy prepared via dealloying method生物相容性的纳米多孔涂层合金镍钛准备通过脱合金法.pdfVIP
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biocompatibility of nanoporous coating on niti alloy prepared via dealloying method生物相容性的纳米多孔涂层合金镍钛准备通过脱合金法
Hindawi Publishing Corporation
Journal of Nanomaterials
Volume 2012, Article ID 731592, 7 pages
doi:10.1155/2012/731592
Research Article
Biocompatibility of Nanoporous TiO2 Coating on
NiTi Alloy Prepared via Dealloying Method
Jin Huang,1 Junqiang Wang,1 Xiangdong Su,2 Weichang Hao,2 Tianmin Wang,2
Yayi Xia,3 Guozu Da,4 and Yubo Fan1
1 Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering,
Beihang University, Beijing 100191, China
2 Center of Material Physics and Chemistry, Beihang University, Beijing 100191, China
3 Orthopedic Institute and The Second Hospital of Lanzhou University, Lanzhou 730030, China
4 Research Division, Gansu Seemine Material High-Tech Co. Ltd., Lanzhou 730030, China
Correspondence should be addressed to Weichang Hao, cmpc@ and Yubo Fan, yubofan@
Received 2 March 2012; Accepted 30 March 2012
Academic Editor: Xiaoming Li
Copyright © 2012 Jin Huang et al. This is an open access article distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This paper investigated the biocompatibility of nanoporous TiO2 coating on NiTi shape-memory alloy (SMA) prepared via
dealloying method. Our previous study shows that the dealloying treatment at low temperature leads to 130 nm Ni-free surface
titania surface layer, which possesses good bioactivity because of the combination of hydroxyl (OH− ) group in the process of
dealloying treatment simultaneously. In this paper, the biological compatibility of NiTi alloy before and after dealloying treatment
was evaluated and compared by direct contact method with dermal mesenchymal stem cells (
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