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bird’s eye view on the recent advances in drug delivery systems鸟瞰在药物输送系统的最新进展
Journal of Biomaterials and Nanobiotechnology, 2011, 2, 544-556
doi:10.4236/jbnb.2011.225065 Published Online December 2011 (/journal/jbnb)
Bird’s Eye View on the Recent Advances in Drug
Delivery Systems
1* 2 3 4
Pramod Vishwanath Prasad , Anand Kumar , Pramod Chandra Pal , Radhey Shyam Sharma ,
3 5 1
Donthamsetty Nageswara Rao , Tulsidas G. Shrivastav , Ren-Shan Ge
1Center for Biomedical Research, Population Council, The Rockefeller University, New York, USA; 2Department of Reproductive
Biology, All India Institute of Medical Sciences, New Delhi, India; 3Department of Biochemistry, All India Institute of Medical Sci-
ences, New Delhi, India; 4Division of RHN, Indian Council of Medical Research, New Delhi, India; 5Department of Reproductive
Biomedicine, National Institute of Health and Family Welfare, New Delhi, India.
* *
E-mail: drpramod.pusa@, pkbiochem@
Received September 5th, 2011; revised October 14th, 2011; accepted November 20th, 2011.
ABSTRACT
Successful treatment of most of the diseases is limited by a lack of safe and effective methods of drug delivery. Drug
delivery methods have significant effects on the pharmacological efficacy of a drug. Every drug has an optimum con-
centration range within which maximum benefit is derived; and concentrations above or below the range can be toxic
or provide no therapeutic benefits at all. Therefore, development of an efficient drug delivery system remains an im-
portant challenge in medicine , and this can be achieved only through multidisciplinary approaches to the mechanisms
of delivery of drugs to targets in tissues. Thus, several drug delivery and drug targeting systems are currently being
developed. Targetin
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