clinical use of estimating glomerular filtration rate equ-ations during pregnancy临床使用估计的肾小球滤过率equ-ations怀孕期间.pdfVIP

Vol.3, No.1, 32-36 (2011) Health doi:10.4236/health.2011.31006 Clinical use of estimating glomerular filtration rate equ- ations during pregnancy 1* 2 1 Luiz Paulo José Marques , Regina Rocco , Maria Helena Victor , Benedita Calheiros de Novaes2 1 1 , Ana Luiza Batista de Carvalho , Omar da Rosa Santos 1Renal Unit of Gaffrèe and Guinle University Hospital-Department of Medicine, Federal University of Rio de Janeiro State, Rio de Janeiro, Brazil; marqueslpj@iG.com.br 2Obstetric Unit of Gaffrèe and Guinle University Hospital-Department of Medicine, Federal University of Rio de Janeiro State, Rio de Janeiro, Brazil Received3 November 2010; revised 5 November 2010; accepted 8 November 2010. ABSTRACT important maternal renal physiological altera- tions and provides the measure of GFR the Background: Kidney disease, even when mild, most unbiased and precise as possible. was once considered so major an impediment to successful pregnancy and so dangerous to Keywords: Pregnancy, Kidney function, the mother’s wellbeing. High-risk pregnancy Glomerular Filtration Rate, MDRD equation, mainly associated to renal impairment may oc- Cockcroft-Gault equation. cur in 10-20% of gestations and it is very im- portant that renal function is closely monitored 1. INTRODUCTION to prevent or minimize maternal an