原创力文档comparing dietary determinants of serum vitamin d status among african-americans and caucasians比较血清维生素d状况的膳食因素在黑人和白人.pdfVIP
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comparing dietary determinants of serum vitamin d status among african-americans and caucasians比较血清维生素d状况的膳食因素在黑人和白人
Open Journal of Epidemiology, 2012, 2, 14-21 OJEpi
/ 10.4236/ojepi.2012.21003 Published Online February 2012 (http://www.SciRP.org/journal/ojepi/)
Comparing dietary determinants of serum vitamin D status
among African-Americans and Caucasians
*
Sameer Murali, Lenore Arab , Alfonso Ang, Casey Nelson, Katherine Wessling-Perry,
Patricia Jardack, Ronald L. Horst
Division of General Internal Medicine, David Geffen School of Medicine at UCLA, Los Angeles, USA
*
Email: larab@
Received 2 November 2011; revised 6 December 2011; accepted 15 December 2011
ABSTRACT 1. INTRODUCTION
African-Americans (AAs) maintain a high prevalence Race is often correlated with socioeconomic factors that
of vitamin D insufficiency compared to Caucasians. differentially impact health outcomes, but rarely is skin
The relationship between dietary sources of vitamin color considered as an independent determinant of
D and serum 25-hydroxyvitamin D (25(OH)D) among health. The inverse relationship between serum vitamin D
AAs remains poorly understood. This research ex- (25(OH)D) status and skin pigmentation represents an
amines the dietary determinants of 25(OH)D levels in exceptional case where physiology is driven by skin color
AAs and Caucasians, controlling for demographic alone [1]. Ninety-seven percent of African-American (AA)
characteristics. 121 Caucasians and 119 AAs partici- adults and adolescents are vitamin D insufficient (20
pated in a biomarker based study, comparing the ng/mL) or def
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