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Internat. J. Math. Math. Sci. Vol. 24, No. 5 (2000) 345–349 S016117120000362 © Hindawi Publishing Corp. DERIVATIONS OF CERTAIN OPERATOR ALGEBRAS JIANKUI LI and HEMANT PENDHARKAR (Received 20 March 199 8and in revised form 2 July 1999) Abstract. Let be a nest and let be a subalgebra of L(H) containing all rank one operators of alg. We give several conditions under which any derivation δ from into L(H) must be inner. The conditions include (1) H− ≠ H , (2) 0+ ≠ 0, (3) there is a nontrivial projection in which is in , and (4) δ is norm continuous. We also give some applications. Keywords and phrases. Derivation, nest algebra, triangular operator algebra. 2000 Mathematics Subject Classification. Primary 47B47, 47L35. 1. Introduction. In this paper, we unify some results on derivations by considering derivations from an algebra containing all rank one operators of a nest algebra into an -bimodule . Chernoff [1] proves that every derivation from F(H) into L(H) is inner. In [2], Christensen proves that every derivation from a nest algebra into itself or into L(H) is inner. In [3], Christensen and Peligrad show that every derivation of a quasitriangular operator algebra into itself is inner. Knowles [7] generalizes the result of [2] and gets that any derivation from a nest algebra into an ideal of L(H) is inner. Let be a nest of subspaces of a Hilbert space H , let be a subalgebra of L(H) containing all rank one operators of alg, and let δ be a derivation from into L(H). We prove that if one of the following conditions holds: (1) H− ≠ H, (2) 0+ ≠ 0, (3) there exists a nontrivial P ∈ , such that P ∈ , then δ is inner. We also prove that for any nest, if δ is a norm continuous derivation from into L(H), then δ is inner. We discuss some applications of these results.