dextran coating on and among fibers of polymer sponge scaffold for osteogenesis by bone marrow cells in vivo葡聚糖涂层和聚合物海绵支架的纤维骨骨髓细胞体内.pdfVIP

J. Biomedical Science and Engineering, 2010, 3, 751-757 JBiSE doi:10.4236/jbise.2010.38100 Published Online August 2010 (http://www.SciRP.org/journal/jbise/). Dextran coating on and among fibers of polymer sponge scaffold for osteogenesis by bone marrow cells in vivo Masataka Yoshikawa1,2 1 1 1 , Norimasa Tsuji , Hideyuki Kakigi , Takayoshi Yabuuchi , Yasunori Shimomura1 1 2 , Hiroyuki Hayashi , Hajime Ohgushi 1Department of Endodontics, Osaka Dental University, Osaka, Japan; 2Tissue Engineering Research Group, Health Research Institute, National Institute of Advanced, Industrial Science and Technology, Amagasaki, Japan. Email: yosikawa@cc.osaka-dent.ac.jp Received 25 May 2010; revised 8 June 2010; accepted 20 June 2010. ABSTRACT technique for differentiation and induce these blast cells from stem cells are not still established. This may be one Although hydroxyapatite is commonly used as a of the reasons that tooth regeneration is not realized. scaffold for bone regeneration, sponges may be suit- Restoration of partial defect of the tooth or reproduction able because of the adaptability to the defect. To use of the whole tooth that had been missed for any reason as a scaffold, the fiber of sponge would be coated with