原创力文档diagnostic accuracy of biochemical markers of fibrosis in black african patients with chronic hepatitis b诊断准确性的生化标记物的非洲黑人慢性乙型肝炎患者的纤维化.pdfVIP
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diagnostic accuracy of biochemical markers of fibrosis in black african patients with chronic hepatitis b诊断准确性的生化标记物的非洲黑人慢性乙型肝炎患者的纤维化
Vol.2, No.12, 1413-1420 (2010) Health
doi:10.4236/health.2010.212210
Diagnostic accuracy of biochemical markers of fibrosis
in black African patients with chronic hepatitis B
1* 1 1
Alassan Kouamé Mahassadi , Alain Koffi Attia , Fulgence M. Yao Bathaix ,
Narcisse Baudouin Agbé1 1 1
, Stanislas Doffou , Henriette Ya Kissi ,
Isidore Mouhenou Diomandé2 3 1
, Paul Cales , Thérese Ndri-Yoman
1Service d’hépato-gastroentérologie, CHU de Yopougon, Abidjan, Côte d’Ivoire; *Corresponding Author: mahassadi@;
2Laboratoire d’anatomie pathologique, Faculté de médecine de Cocody, Abidjan, Côte d’Ivoire;
3Service d’hépato-gastroentérologie, CHU d’Angers, France.
Received 15 August 2010; revised 6 October 2010; accepted 11 October 2010
ABSTRACT able markers to exclude significant fibrosis or
more accurately cirrhosis in black African pa-
Contradictory results of the accuracy of bio- tients with CHB.
chemical markers to predict the stage of fibrosis
in black African patients with chronic hepatitis B Keywords: Non Invasive Models; Fibrosis;
(CHB) were previously published. We con- Cirrhosis; Hepatitis B; Sub-Saharan Africa
ducted a prospective cohort study to determine
the diagnostic accuracy of aspartate aminotrans- 1. INTRODUCTION
ferase to platelet ratio (APRI), aspartate ami-
notransfe
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