difference of the pain during the dpt (diphtheria-pertussis-tetanus) vaccination差异的痛苦在dpt的百白破疫苗接种.pdfVIP

World Journal of Vaccines, 2012, 2, 91-95 91 /10.4236/wjv.2012.22012 Published Online May 2012 (http://www.SciRP.org/journal/wjv) Difference of the Pain during the DPT * (Diphtheria-Pertussis-Tetanus) Vaccination Yuichirou Tsuji1,2#, Izumi Ichihashi1,2, Kouji Morita1,2, Kazuo Itabashi2 1Pediatrics, Sempos Tokyo Takanawa Hospital, Tokyo, Japan; 2Department of Pediatrics, School of Medicine, Showa University, Tokyo, Japan. Email: #yuitsuji@ybb.ne.jp Received March 25th, 2012; revised April 22nd, 2012; accepted May 10th, 2012 ABSTRACT Background: The objective of this study is to determine whether analyze of the infant’s pain associated with diphthe- ria-pertussis-tetanus (DPT) immunization is useful for vaccination in children. It is not known whether the immuniza- tion pain can be prevented with the adequate choice of DPT vaccines among several manufacturers in Japan. Further, it is not clear whether the difference of the reaction during vaccination between gender and age. Design: Three manufac- turer’s Japanese DPT vaccines were used in this study. The parents assessed their infant’s pain on a modified visual analogue scale (MVAS), the start of the crying and total crying time during the immunization. Results: The A manu- facturer’s DPT vaccine was significantly lower on the proportion of crying, the duration of crying and MVAS score than the other two manufacturer’s DPT vaccines. The proportion of crying, the duration of crying and MVAS score was lower in the boy than in the girl. On the other hand, it had not found the difference of their reactions with age. Conclu- sions: Our studies have found that the adequate choice of DPT vaccine decreased vaccination pain. The studies also indicate that some tendencies with vaccinations