effectiveness of eeg biofeedback as compared with methylphenidate in the treatment of attention-deficithyperactivity disorder a cinical out-come study脑电生物反馈的有效性与哌醋甲酯治疗attention-deficithyperactivity障碍cinical成果研究.pdfVIP
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effectiveness of eeg biofeedback as compared with methylphenidate in the treatment of attention-deficithyperactivity disorder a cinical out-come study脑电生物反馈的有效性与哌醋甲酯治疗attention-deficithyperactivity障碍cinical成果研究
Neuroscience Medicine, 2011, 2, 78-86
doi:10.4236/nm.2011.22012 Published Online June 2011 (http://www.SciRP.org/journal/nm)
Effectiveness of EEG Biofeedback as Compared
with Methylphenidate in the Treatment of
Attention-Deficit/Hyperactivity Disorder: A
Clinical Outcome Study
1,2 2 2 2
Mohammad Ali Nazari , Laurent Querne , Alain De Broca , Patrick Berquin
1 2
Department of Psychology, University of Tabriz, Tabriz, Iran; Department of Paediatric Neurology, Lab. Neurosciences Fonction-
nelles Pathologies, Amiens, France.
Email: alinazari@tabrizu.ac.ir
Received March 13th, 2010; revised March 23rd, 2011; accepted April 25th, 2011.
ABSTRACT
Operant conditioning of the electroencephalographic rhythm (EEG biofeedback) is argued to be an effective method for
treating children with ADHD. This study was designed to evaluate whether this method, compared to methylphenidate,
achieves an equally effective outcome. Participants were 39 children aged between 7 - 12 years. Thirteen children with
attention-deficit/hyperactivity disorder (ADHD) were trained to enhance the amplitude of the beta1 activity (15 - 18 Hz)
and decrease the amplitude of the theta activity (4 - 8 Hz), and 13 of which were treated with methylphenidate alone.
Thirteen healthy children did not receive intervention. Several behavioral, neuropsychological and experimental tests
were administered before and after intervention. While behavioral measures were improved by both types of method,
methylphenidate was significantly more effective than EEG biofeedback. Response inhibition was improved only by
EEG biofeedback . Both EEG biofeedback and methylphenidate were associated with improvements on the variability
and accuracy measures of computerized tests. Intellectual ability increased
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