effects of diet, aerobic exercise, or both on non-hdl-c in adults a meta-analysis of randomized controlled trials影响饮食,有氧运动,或两者在成人non-hdl-c随机对照试验的荟萃分析.pdfVIP

Hindawi Publishing Corporation Cholesterol Volume 2012, Article ID 840935, 5 pages doi:10.1155/2012/840935 Research Article Effects of Diet, Aerobic Exercise, or Both on Non-HDL-C in Adults: A Meta-Analysis of Randomized Controlled Trials George A. Kelley and Kristi S. Kelley Meta-Analytic Research Group, Department of Biostatistics, School of Public Health, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV 26506-9190, USA Correspondence should be addressed to George A. Kelley, gkelley@ Received 18 August 2012; Accepted 26 September 2012 Academic Editor: Jan Wouter Jukema Copyright © 2012 G. A. Kelley and K. S. Kelley. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Purpose. To use the meta-analytic approach to examine the effects of diet (D), aerobic exercise (E), or both (DE) on non-high- density lipoprotein cholesterol (non-HDL-C) in adults. Methods. Randomized controlled trials in adults ≥18 years of age were included. A mixed-effect model was used to combine effect size (ES) results within each subgroup and to compare subgroups (Qb ). Heterogeneity was examined using the Q and I 2 statistics, and 95% confidence intervals (CI) were also calculated. Statistical significance was set at P ≤ 0.05, while a trend for statistical significance was set between P 0.05, and ≤0.10. Results. A statistically significant exercise minus control group decrease in non-HDL-C was found for DE (7 ESs, 389 participants, x = −11.1 mg/dL, 95% CI = −21.7 to −0.6, P = 0.04, Q = 2.4, P = 0.88, I 2 = 0%), a trend for the D group (7 ESs, 402 participants, x = −8.5 mg/dL, 95% CI = −18.6