脑肿瘤对大脑皮层运动区BOLD-fMRI信号的影响.docVIP

脑肿瘤对大脑皮层运动区BOLD-fMRI信号的影响 #（400016重庆， [摘要] 目的 采用血氧依赖水平功能磁共振成像（BOLD-fMRI）技术，探讨不同类型、性质、起源的脑肿瘤对大脑皮层运动区BOLD-fMRI信号激活范围强度 方法临近或累及的脑肿瘤患者获得功能区BOLD激活图像分析MRI信号范围强度与脑肿瘤间的关系20.50，SM Ⅰ:29.89±16.27；强度：M Ⅰ：29.56±21.42，SM Ⅰ:23.64±10.31），良性脑肿瘤组信号范围及强度（范围：M Ⅰ：110.20±50.68，SM Ⅰ:77.89±18.55；强度：M Ⅰ：46.65±13.21，SM Ⅰ:38.21±13.25），非肿瘤组信号范围及强度（范围：M Ⅰ：183.45±43.95，SM Ⅰ:180.46±30.28；强度：M Ⅰ：65.13±16.55，SM Ⅰ:65.64±11.87）。3组间信号范围及强度差异明显（P＜0.05）。脑功能区成像范围与强度呈正相关（M Ⅰ：R2= 0.56，P0.05；SM Ⅰ: R2= 0.41，P0.05）。结论较高 [关键词脑肿瘤BOLD-fMRI The influence of the BOLD-fMRI signal with brain tumors in the brain cortex motor area Gao Chao, Zhan Ao, Xie Yanfeng, Shi Quanhong（Department of Neurosurgery, the First Affiliated Hospital of Chongqing Medical University, NO.1 Youyi Rode,Chongqing 400016,China） [Abstract] Objective To discuss different types, nature, origin of brain tumors with the influence of the blood oxygen level functional magnetic resonance imaging (BOLD-fMRI) signal in the cerebral cortex motor area, including the strength and the scope. Methods Retrospective study of 48 patients with neighboring or cumulative movement cerebral cortex brain tumors (malignant 27 cases, 21 cases of benign) and 10 cases without brain tumors. Obtain the function BOLD activation images of motor cortex, analyzing the motion function of cerebral cortex BOLD fMRI signal with strength and scope and the relationship between different brain tumors. Results Signal range and intensity of malignant brain tumor group (range: M Ⅰ: 51.07±20.50, SM Ⅰ:29.89±16.27; strength: M Ⅰ:29.56±21.42, SM Ⅰ:23.64±10.31), the signal range and intensity of benign brain tumor group (range: M Ⅰ:110.20±50.68, SM Ⅰ:77.89 ±18.55; strength: M Ⅰ:46.65±13.21, SM Ⅰ:38.21±13.25), the signal range and intensity of non-tumor group (range: M Ⅰ:183.45±43.95, SM Ⅰ:180.46±30.28; strength: M Ⅰ:65.13±16.55, SM Ⅰ:65.64±11.87). Results of the signal range and intensity in three groups is different (P0.05). Brain function imaging range and intensity were positively correl