a v530i mutation in c-kit exon 10 is associated to imatinib response in extraabdominal aggressive fibromatosisc - kit v530i突变的外显子10 extraabdominal伊马替尼反应积极的纤维瘤病有关.pdfVIP
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a v530i mutation in c-kit exon 10 is associated to imatinib response in extraabdominal aggressive fibromatosisc - kit v530i突变的外显子10 extraabdominal伊马替尼反应积极的纤维瘤病有关
Hindawi Publishing Corporation
Sarcoma
Volume 2010, Article ID 458156, 4 pages
doi:10.1155/2010/458156
Case Report
A V530I Mutation in c-KIT Exon 10 Is Associated to Imatinib
Response in Extraabdominal Aggressive Fibromatosis
1 ` 1 2 ` 3
Jean-Emmanuel Kurtz, Irene Asmane, Anne-Claire Voegeli, Agnes Neuville,
4 ` 1 5 1
Armelle Dufresne, Valere Litique, Christine Chevreau, and Jean-Pierre Bergerat
1 Pole d’Hematologie et d’Oncologie, Hopitaux Universitaires de Strasbourg, 67098 Strasbourg, France
ˆ ´ ˆ
2 Pole de Biologie, Hopitaux Universitaires de Strasbourg, 67098 Strasbourg, France
ˆ ˆ
3 Service d’Anatomie pathologique, Hopitaux Universitaires de Strasbourg, 67098 Strasbourg, France
ˆ
4 Service d’Oncologie Medicale, Centre Hospitalier de Chambery, 73011, France
´ ´
5 Service d’Oncologie Medicale, Centre Hospitalier Universitaire, 31052 Toulouse, France
´
Correspondence should be addressed to Jean-Emmanuel Kurtz, j-emmanuel.kurtz@chru-strasbourg.fr
Received 5 October 2009; Revised 4 January 2010; Accepted 25 January 2010
Academic Editor: Irene Andrulis
Copyright © 2010 Jean-Emmanuel Kurtz et al. This is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any mediu
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