basal cell carcinoma of the head and neck region in ethnic chinese基底细胞癌华人的头部和颈部区域.pdfVIP

Hindawi Publishing Corporation International Journal of Surgical Oncology Volume 2011, Article ID 890908, 7 pages doi:10.1155/2011/890908 Clinical Study Basal Cell Carcinoma of the Head and Neck Region in Ethnic Chinese Velda Ling Yu Chow, Jimmy Yu Wai Chan, Richie Chiu Lung Chan, Joseph Hon Ping Chung, and William Ignace Wei Division of Head and Neck, Plastic and Reconstructive Surgery, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Hong Kong Correspondence should be addressed to Velda Ling Yu Chow, vlychow@ Received 1 May 2011; Revised 4 June 2011; Accepted 8 June 2011 Academic Editor: Michael Veness Copyright © 2011 Velda Ling Yu Chow et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objectives. This study aims to report our experience in the management of HNBCC in ethnic Chinese over a 10-year period. Methods. A retrospective review of all ethnic Chinese patients with HNBCC treated in a tertiary centre from 1999 to 2009. Results. From 1999 to 2009, 225 patients underwent surgical excision for HNBCC. Majority were elderly female patients. Commonest presentation was a pigmented (76.2%) ulcer (64.8%) over the nose (31.6%). Median skin margin taken on tumour excision was 2.0 mm; primary skin closure was achieved in 51.8%. Postresection skin margin was clear in 75.4%. Of those with inadequate skin margins, 56.7% opted for further treatment, 43.4% for observation. Recurrence rates were 2.6% and 13.8%, respectively (P = 0.106). Overall recurrence rate was 5.5%. Conclusions. HNBCC commonly presented as pigmented ulcers over the nose of elderl