centella asiatica improves physical performance and health-related quality of life in healthy elderly volunteer积雪草的改善物理性能和健康相关的生活质量健康的老年志愿者.pdfVIP

Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2011, Article ID 579467, 7 pages doi:10.1093/ecam/nep177 Original Article Centella asiatica Improves Physical Performance and Health-Related Quality of Life in Healthy Elderly Volunteer Lugkana Mato,1 Jintanaporn Wattanathorn,2 Supaporn Muchimapura,2 Terdthai Tongun,2 Nawanant Piyawatkul,3 Kwanchanok Yimtae,4 Panida Thanawirattananit,4 and Bungorn Sripanidkulchai5 1 Department of Biomedical Science Program, Graduate School, Khon Kaen University, 40002, Thailand 2 Department of Physiology, Faculty of Medicine, Khon Kaen University, 40002, Thailand 3 Department of Psychiatry, Faculty of Medicine, Khon Kaen University, 40002, Thailand 4 Department of Otolaryngology, Faculty of Medicine, Khon Kaen University, 40002, Thailand 5 Center for Research and Development of Herbal Health Product, Faculty of Pharmaceutical Sciences, Khon Kaen University 40002, Thailand Correspondence should be addressed to Jintanaporn Wattanathorn, jintanapornw@ Received 15 July 2009; Accepted 3 October 2009 Copyright © 2011 Lugkana Mato et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Recently, oxidative stress has been reported to contribute an important role in the decline of physical function as age advances. Numerous antioxidants can improve both physical and psychological performances resulting in the increase of health-related quality of life (HQOL). Therefore, we hypothesized that Centella asiatica, a medicinal plant reputed for nerve tonic, strength improvement and antioxidant activity, c