canadian pregnancy outcomes in rheumatoid arthritis and systemic lupus erythematosus加拿大的妊娠结果在类风湿性关节炎和系统性红斑狼疮.pdfVIP

Hindawi Publishing Corporation International Journal of Rheumatology Volume 2011, Article ID 345727, 6 pages doi:10.1155/2011/345727 Research Article Canadian Pregnancy Outcomes in Rheumatoid Arthritis and Systemic Lupus Erythematosus Cheryl Barnabe,1 Peter D. Faris,2 and Hude Quan3 1 Department of Medicine, University of Calgary, Calgary, AB, Canada T2N 4N1 2 Alberta Bone Joint Health Institute, Calgary, AB, Canada T2N 4Z6 3 Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada T2N 4N1 Correspondence should be addressed to Cheryl Barnabe, ccbarnab@ucalgary.ca Received 29 July 2011; Accepted 15 August 2011 Academic Editor: Shinichi Kawai Copyright © 2011 Cheryl Barnabe et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. To describe obstetrical and neonatal outcomes in Canadian women with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE). Methods. An administrative database of hospitalizations for neonatal delivery (1998–2009) from Calgary, Alberta was searched to identify women with RA (38 pregnancies) or SLE (95 pregnancies), and women from the general population matched on maternal age and year of delivery (150 and 375 pregnancies, resp.). Conditional logistic regression was used to calculate odds ratios (OR) for maternal and neonatal outcomes, adjusting for parity. Results. Women with SLE had increased odds for preeclampsia or eclampsia (SLE OR 2.16 (95% CI 1.10–4.21; P = 0.024); RA OR 2.33 (95% CI 0.76–7.14; P = 0.138)). Women with SLE had increased odds for cesarean section after adjustment for dysfu