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Hindawi Publishing Corporation Journal of Oncology Volume 2010, Article ID 736907, 10 pages doi:10.1155/2010/736907 Research Article Significant Growth Inhibition of Canine Mammary Carcinoma Xenografts following Treatment with Oncolytic Vaccinia Virus GLV-1h68 Ivaylo Gentschev,1, 2 Klaas Ehrig,2 Ulrike Donat,2 Michael Hess,2 Stephan Rudolph,2 1 1 1 ¨ 3, 4 4 1, 2 Nanhai Chen, Yong A. Yu, Qian Zhang, Jorn Bullerdiek, Ingo Nolte, Jochen Stritzker, and Aladar A. Szalay1, 2, 5, 6, 7 1 Genelux Corporation, San Diego Science Center, San Diego, CA 92109, USA 2 Department of Biochemistry, University of Wuerzburg, 97074 Wuerzburg, Germany 3 Center for Human Genetics, University of Bremen, 28359 Bremen, Germany 4 Small Animal Clinic, University of Veterinary Medicine, Bischofsholer Damm 15, 30173 Hannover, Germany 5 Rudolf Virchow Center for Experimental Biomedicine, University of Wuerzburg, 97078 Wuerzburg, Germany 6 Institute for Molecular Infection Biology, University of Wuerzburg, 97078 Wuerzburg, Germany 7 Department of Radiation Oncology, Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive 0843, La Jolla, CA 92093-0843, USA Correspondence should be addressed to Aladar A. Szalay, aaszalay@ Received 28 August 2009; Revised 18 February 2010; Accepted 11 May 2010 Academic Editor: Dominic Fan Copyright © 2010 Ivaylo Gentschev et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.