selection of spatiotemporal features in breast mri to differentiate between malignant and benign small lesions using computer-aided diagnosis选择乳腺mri的时空特性区分使用计算机辅助诊断恶性和良性小病灶.pdfVIP

Hindawi Publishing Corporation Advances in Artificial Neural Systems Volume 2012, Article ID 919281, 8 pages doi:10.1155/2012/919281 Research Article Selection of Spatiotemporal Features in Breast MRI to Differentiate between Malignant and Benign Small Lesions Using Computer-Aided Diagnosis F. Steinbruecker,1 A. Meyer-Baese,2 C. Plant,2 T. Schlossbauer,3 and U. Meyer-Baese4 1 Department of Computer Science, Technical University of Munich, 8574 Garching, Germany 2 Department of Scientific Computing, Florida State University, Tallahassee, FL 32306-4120, USA 3 Institute for Clinical Radiology, University of Munich, 81377 Munich, Germany 4 Department of Electrical and Computer Engineering, FAMU/FSU College of Engineering, Tallahassee, FL 32310-6046, USA Correspondence should be addressed to A. Meyer-Baese, ameyerbaese@ Received 29 February 2012; Accepted 14 May 2012 Academic Editor: Juan Manuel Gorriz Saez Copyright © 2012 F. Steinbruecker et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Automated detection and diagnosis of small lesions in breast MRI represents a challenge for the traditional computer-aided diagnosis (CAD) systems. The goal of the present research was to compare and determine the optimal feature sets describing the morphology and the enhancement kinetic features for a set of small lesions and to determine their diagnostic performance. For each of the small lesions, we extracted morphological and dynamical features describing both global and local shape, and kinetics behavior. In this paper, we compare the performance of each extracted feature set for the diffe