平消胶囊治疗乳腺增生病临床观察.docVIP

平消胶囊治疗乳腺增生病临床观察[摘要] 目的:探讨平消胶囊在乳腺增生病治疗中的疗效。方法:将我科门诊2007年2～8月328例乳腺增生病患者随机分为两组,治疗组172例,口服平消胶囊治疗;对照组156例,应用乳康片治疗。结果:治疗组乳房疼痛缓解和乳房肿块缩小,总有效率明显高于对照组。结论:在乳腺增生病的治疗方面,平消胶囊疗效显著,副作用少,值得临床应用。 [关键词] 平消胶囊;乳腺增生病;临床观察 [中图分类号] R655.8[文献标识码] A[文章编号]1673-7210(2010)05(a)-091-02 Clinicalobservation ofPingxiao Capsule in treatment ofmammoplasia CHANG Qinglong, JIA Guocong, FENG Aiqiang, ZHANG Yanwu (Department of Mamatary in the Third Affiliated Hospital of Zhengzhou University, ZhengZhou450052, China) [Abstract] Objective: To investigate the effect of Pingxiao Capsule in treatment of mammoplasia. Methods: 328 cases ofpariengs with mammoplasia were randomly divided into two groups from February to August 2007 in our department, the treatment group, 172 cases of oral Pingxiao Capsule , the control group, 156 cases of oral Rukang Capsule. Results: Lumps of breast reduced and pain of breast was relieved in the treatment group and the total effective rate was significantly higher in the treatment group than that in the control group. Conclusion: Pingxiao Capsule has a significant effect and less side effects in the treatment of mammoplasia. It is worth of clinical application. [Key words] Pingxiao Capsule; Mammoplasia; Clinical observation 乳腺增生病是女性的常见病,好发于30～50岁。常表现为乳房疼痛,经前期为重,乳房可触及结节或肿块,严重者可影响患者的日常生活、工作,而且本病易复发,常合并妇科疾病。部分病例可演变为乳腺癌,危及患者的生命。我科应用西安正大制药厂生产的平消胶囊治疗乳腺增生病患者,疗效满意,现报道如下: 1 资料与方法 1.1 一般资料 328例患者为我科2007年2～8月门诊患者,所有患者经过临床检查、乳房彩超或钼靶诊断为乳腺增生病。患者年龄24～52岁,平均病程1.5年,均为女性。按随机原则分为治疗组和对照组。治疗组172例,平均年龄41岁,平均病程1.6年;对照组156例,平均年龄39岁,平均病程1.4年。两组病例平均年龄、平均病程无显著性差异P0.05,具有可比性。 1.2 临床特点 乳房周期性疼痛和肿块是常见的主要症状[1]。疼痛可为刺痛、胀痛、钝痛等,也可放射至肩部、背部。疼痛具有一定规律性,以经前期为重,经后好转或缓解。病情重且病程长者,疼痛表现为持续性或不规律性。临床检查乳房内可触及颗粒状或条状质韧结节,边界不清,有压痛。 1.3 诊断标准 有乳房周期性疼痛和肿块表现者,乳房彩超显示[2]乳腺结构紊乱,回声不均者,且排除其他病变者。 1.4 治疗方法 治疗组采用西安正大制药厂的平消胶囊口服,每次6粒,餐后服用,每日3次,经期前3 d停用,60 d为1个疗程。对照组口服乳康片,每次3片,每日3次,60 d为1个疗程。 1.5 疗效评定标准 治愈:疼痛及肿块消失,彩超显示乳腺回声均匀,无结构紊乱。显效:疼痛明显减轻,肿块明显变小,彩超显示乳腺部分结构紊乱与回声不均。有效:疼痛减轻,肿块变小,彩超示乳腺结构紊