金属罐内壁涂层三聚氰胺类物质的迁移研究.docVIP

编号 论文 题目：学院 专业 学 号 学生姓名 指导教师 二〇一二年月 摘 要[1].金属罐内壁涂层中含有三聚氰胺类物质，这些物质对人体是有害的，近年来受到人们的关注. 液相色谱-质谱联用技术以液相色谱作为分离系统，质谱作为检测系统，经纯化后的样品在液相色谱和质谱部分经过分离和离子化，经由检测器得到质谱图.液质联用体现了色谱和质谱优势的互补，结合了色谱对复杂样品的高分离能力和质谱的高选择性，高灵敏度及能够提供相对分子量和结构信息的优点，在药物分析，食品检测等领域有广泛的应用. 本课题主要研究了三聚氰胺及三聚氰胺衍生物的前处理方法，利用液相色谱串联质谱法测定金属罐内壁涂层三聚氰胺类物质的迁移.研究结果表明，液相色谱串联质谱法测定金属罐内壁涂层三聚氰胺的迁移是可行的，但对于三聚氰胺衍生物，则需要进一步的研究. 关键词：食品安全；三聚氰胺；迁移； ABSTRACT Metal cans are one of the most common food containers, in the milk powder, canned fish especially beverage field widely. In recent years, countries in the world especially the United States, European Union, Japan and other developed countries analysis and the results show that, in contact with food utensils, Kitchenware and packaging containers and packaging materials of harmful elements in harmful substances, has become one of the most important sources of food contamination, food safety has become a new focus to the people.In recent years, people pay attention to the inner wall of the metal tank coating containing melamine substances, these substances are harmful to the human body. Liquid chromatography - mass spectrometry technology in liquid chromatography as separation system, mass spectrometry as a detection system, the purified sample in liquid chromatography and mass spectrometry after separation and ionization part, through the detector obtained by mass spectrometry. LC-MS embodiment of chromatography and mass spectrometry the complementary advantages, combined with the determination of complex samples high separation ability of mass spectrometry and high selectivity, high sensitivity and can provide relative molecular weight and structure information advantages, in pharmaceutical analysis, food detection and other fields have a wide range of applications. This thesis mainly studies the melamine and melamine derivatives of pretreatment methods, using liquid chromatography tandem mass spectrometry method for the determination of the inner wall