changes in weight, waist circumference and compensatory responses with different doses of exercise among sedentary, overweight postmenopausal women改变体重,腰围和补偿性响应不同剂量的锻炼在久坐不动的,超重的绝经后妇女.pdfVIP

Changes in Weight, Waist Circumference and Compensatory Responses with Different Doses of Exercise among Sedentary, Overweight Postmenopausal Women 1 1 1 1 2 Timothy S. Church *, Corby K. Martin , Angela M. Thompson , Conrad P. Earnest , Catherine R. Mikus , Steven N. Blair3 1 Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, United States of America, 2 Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri, United States of America, 3 Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America Abstract Background: It has been suggested that exercise training results in compensatory mechanisms that attenuate weight loss. However, this has only been examined with large doses of exercise. The goal of this analysis was to examine actual weight loss compared to predicted weight loss (compensation) across different doses of exercise in a controlled trial of sedentary, overweight or obese postmenopausal women (n = 411). Methodology/Principal Findings: Participants were randomized to a non-exercise control (n = 94) or 1 of 3 exercise groups; exercise energy expenditure of 4 (n = 139), 8 (n = 85), or 12 (n = 93) kcal/kg/week (KKW). Training intensity was set at the heart rate associated with 50% of each woman’s peak VO2 and the intervention period was 6 months. All exercise was supervised. The main outcomes were actual weight loss, predicted weight loss (exercise energy expenditure/ 7700 kcal per kg), compensation (actual minus predicted weight loss) and waist circumference. The study sample had a mean (SD) age 57.2 (6.3) years, BMI of 31.7 (3.8) kg/m2, and was 63.5% Caucasian. T