coordinated optimization of visual cortical maps (ii) numerical studies协调优化视觉皮质地图(ii)的数值研究.pdfVIP

Coordinated Optimization of Visual Cortical Maps (II) Numerical Studies 1,2,3,4 1,5 ¨ 3,6 7 5,8 Lars Reichl *, Dominik Heide , Siegrid Lowel , Justin C. Crowley , Matthias Kaschube , Fred Wolf1,2,3,4,9* ¨ ¨ 1 Max-Planck-Institute for Dynamics and Self-Organization, Gottingen, Germany, 2 Bernstein Center for Computational Neuroscience, Gottingen, Germany, 3 Bernstein ¨ ¨ Focus Neurotechnology, Gottingen, Germany, 4 Faculty of Physics, Georg-August University, Gottingen, Germany, 5 Frankfurt Institute of Advanced Studies, Frankfurt, ¨ Germany, 6 School of Biology, Georg-August University, Gottingen, Germany, 7 Carnegie Mellon University, Department of Biological Sciences, Pittsburgh, Pennsylvania, United States of America, 8 Physics Department and Lewis-Sigler Institute, Princeton University, Princeton, New Jersey, United States of America, 9 Kavli Institute for Theoretical Physics, University of California, Santa Barbara, California, United States of America Abstract In the juvenile brain, the synaptic architecture of the visual cortex remains in a state of flux for months after the natural onset of vision and the initial emergence of feature selectivity in visual cortical neurons. It is an attractive hypothesis that visual cortical architecture is shaped during this extended period of juvenile plasticity by the coordinated optimization of multiple visual cortical maps such as orientation preference