diabetes is the main factor accounting for hypomagnesemia in obese subjects糖尿病是会计的主要因素在肥胖受试者低镁症.pdfVIP

Diabetes Is the Main Factor Accounting for Hypomagnesemia in Obese Subjects 1 2 ´ 2 ´3 Albert Lecube *, Juan Antonio Baena-Fustegueras , Jose Manuel Fort , Dolors Pelegrı , Cristina ´ 1 ´ 1 Hernandez , Rafael Simo ´ 1 CIBER de Diabetes y Enfermedades Metabolicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Diabetes and Metabolism Research Unit, Institut de Recerca i ` Hospital Universitari Vall d’Hebron (VHIR), Endocrinology Department, Universitat Autonoma de Barcelona, Barcelona, Spain, 2 Endocrinology Surgery Unit, General ` Surgery Department, Hospital Universitari Vall d’Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain, 3 Biochemistry Department, Hospital Universitari Vall ` d’Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain Abstract Objective: Type 2 diabetes (T2DM) and obesity are associated with magnesium deficiency. We aimed to determine whether the presence of type 2 diabetes and the degree of metabolic control are related to low serum magnesium levels in obese individuals. Methods: A) Case-control study: 200 obese subjects [50 with T2DM (cases) and 150 without diabetes (controls)] prospectively recruited. B) Interventional study: the effect of bariatric surgery on serum magnesium levels was examined in a subset of 120 obese subjects (40 with type 2 diabetes and 80 without diabet