genotypic homogeneity of multidrug resistant s. typhimurium infecting distinct adult and childhood susceptibility groups in blantyre, malawi基因型耐药金黄色的同质性沙门氏菌感染感染不同的成人和儿童在布兰太尔敏组,马拉维.pdfVIP

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genotypic homogeneity of multidrug resistant s. typhimurium infecting distinct adult and childhood susceptibility groups in blantyre, malawi基因型耐药金黄色的同质性沙门氏菌感染感染不同的成人和儿童在布兰太尔敏组,马拉维.pdf

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genotypic homogeneity of multidrug resistant s. typhimurium infecting distinct adult and childhood susceptibility groups in blantyre, malawi基因型耐药金黄色的同质性沙门氏菌感染感染不同的成人和儿童在布兰太尔敏组,马拉维

Genotypic Homogeneity of Multidrug Resistant S. Typhimurium Infecting Distinct Adult and Childhood Susceptibility Groups in Blantyre, Malawi 1,2 4 8 3 Chisomo L. Msefula *, Robert A. Kingsley , Melita A. Gordon , Elizabeth Molyneux , 2,5,9 6,7 4 2 Malcolm E. Molyneux , Calman A. MacLennan , Gordon Dougan , Robert S. Heyderman 1 Department of Microbiology, College of Medicine, University of Malawi, Blantyre, Malawi, 2 Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MLW), College of Medicine, University of Malawi, Blantyre, Malawi, 3 Department of Paediatrics, College of Medicine, University of Malawi, Blantyre, Malawi, 4 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, 5 University of Liverpool, Liverpool, United Kingdom, 6 Novartis Vaccines Institute for Global Health S.r.l. (NVGH), Siena, Italy, 7 MRC Centre for Immune Regulation, School of Immunity and Infection, College of Medicine and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom, 8 Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom, 9 Department of Medicine, College of Medicine, University of Malawi, Blantyre, Malawi Abstract Nontyphoidal Salmonella (NTS) serovars are a common cause of bacteraemia in young children and HIV-infected adults in Malawi and elsewhere in sub-Saharan Africa. These patient populations provide diverse host-immune environments that have the potential to drive bacterial adaptation and evolution. We therefore investi