serum fsh levels in coasting programmes on the hcg day and their clinical outcomes in ivf ± icsi cycles血清fsh水平滑行项目及其在体外受精临床结果的线天±icsi周期.pdfVIP

Hindawi Publishing Corporation International Journal of Endocrinology Volume 2012, Article ID 540681, 7 pages doi:10.1155/2012/540681 Clinical Study Serum FSH Levels in Coasting Programmes on the hCG Day and Their Clinical Outcomes in IVF ± ICSI Cycles Srisailesh Vitthala,1 Jerome Bouaziz,2 Amanda Tozer,3 Ariel Zosmer,3 and Talha Al-Shawaf3 1 Kamineni Fertility Centre, Kamineni Hospitals, King Koti, Hyderabad 500001, India 2 Services of Gynecology and Obstetrics-Reproduction, The Bow Hospital, Chu de Nice, Route Saint Anton, 06200 Nice, France 3 Centre for Reproductive Medicine-Barts and The London NHS Trust, London EC 1A 7BE, UK Correspondence should be addressed to Srisailesh Vitthala, vittsri@ Received 28 July 2011; Revised 12 October 2011; Accepted 17 October 2011 Academic Editor: Mario Maggi Copyright © 2012 Srisailesh Vitthala et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Introduction. Coasting is the most commonly used strategy in prevention of severe OHSS. Serum FSH levels measurements during coasting may aid in optimizing the duration of coasting. Objective(s). To study live birth rates (LBRs), clinical pregnancy rates (CPRs), and optimal duration of coasting based on serum FSH levels on the hCG day. Materials and Methods. It is a retrospective study performed between 2005 and 2008 at Barts and The London Centre for Reproductive Medicine, NHS Trust, London, UK, on 349-coasted women undergoing controlled ovarian stimulation (COS) for IVF ± ICSI. The serum FSH level measurements on the hCG day during coasting programme were analysed to predict the LBR and CPR. Result(s). LBR and CPR were si