serum galactose-deficient iga1 level is not associated with proteinuria in children with iga nephropathy血清galactose-deficient iga1水平不iga肾病患儿伴有蛋白尿.pdfVIP

Hindawi Publishing Corporation International Journal of Nephrology Volume 2012, Article ID 315467, 7 pages doi:10.1155/2012/315467 Research Article Serum Galactose-Deficient IgA1 Level Is Not Associated with Proteinuria in Children with IgA Nephropathy M. Colleen Hastings,1, 2, 3 Sabahat Afshan,1, 2 John T. Sanders,4 Oulimata Kane,1, 2 T. Matthew Eison,1, 2 Keith K. Lau,5 Zina Moldoveanu,6 Bruce A. Julian,6, 7 Jan Novak,6 and Robert J. Wyatt1, 2 1 Children’s Foundation Research Institute, Le Bonheur Children’s Hospital, 50 North Dunlap, Memphis, TN 38103-2893, USA 2 Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Memphis, TN 38103, USA 3 Department of Medicine, University of Tennessee Health Science Center, 956 Court Avenue, Memphis, TN 38163, USA 4 Sanford Children’s Hospital Sioux Falls, 1305 W 18th Street, Sioux Falls, SD 57117-5039, USA 5 Department of Pediatrics, McMaster University, 1280 Main Street, West Hamilton, ON, Canada L8S 4K1 6 Department of Microbiology, University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL 35294, USA 7 Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, AL 35294, USA Correspondence should be addressed to M. Colleen Hastings, mhasting@ Received 8 February 2012; Accepted 13 April 2012 Academic Editor: Omran Bakoush Copyright © 2012 M. Colleen Hastings et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Introduction. Percentage of galactose-deficient IgA1 (Gd-IgA1) relative to total IgA in serum was recently reported to