the role of endoplasmic reticulum stress in autoimmune-mediated beta-cell destruction in type 1 diabetes内质网应激的作用在谷蛋白β细胞破坏1型糖尿病.pdfVIP

Hindawi Publishing Corporation Experimental Diabetes Research Volume 2012, Article ID 238980, 12 pages doi:10.1155/2012/238980 Review Article The Role of Endoplasmic Reticulum Stress in Autoimmune-Mediated Beta-Cell Destruction in Type 1 Diabetes Jixin Zhong,1, 2, 3 Xiaoquan Rao,2, 3 Jun-Fa Xu,4 Ping Yang,1, 2 and Cong-Yi Wang1, 2, 4 1 The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, China 2 The Center for Biotechnology and Genom