血清BNP,cTnI及心肌酶谱水平检测在心力衰竭患者中的应用价值.PDFVIP

海南医学2013 年1 月第24 卷第1 期 Hainan Med J, Jan. 2013, Vol. 24, No. 1 doi:10.3969/j.issn.1003-6350.2013.01.0023 ·论 著· 血清BNP 、cTnI 及心肌酶谱水平检测 在心力衰竭患者中的应用价值 岳燕军，董存元，陈素娟 （河北北方学院附属第三医院检验科，河北 张家口 075000 ） 【摘要】 目的 探讨血清脑钠肽（BNP ）、心肌肌钙蛋白I （cTnI ）及心肌酶谱水平检测在心力衰竭患者中的应 用价值。方法 选取2010 年8 月至2012 年4 月于本院进行治疗的58 例心力衰竭患者为观察组，同期进行体检的 58 名健康体检者为对照组，将观察组不同分级及类型患者和对照组患者的血清BNP 、cTnI 及心肌酶谱水平进行 检测及比较。结果 观察组患者血清BNP 、cTnI 及心肌酶谱指标均高于对照组，且NYHA 分级高者水平高于分 级低者，混合性心衰及收缩性心衰者高于舒张性心衰患者（P均＜0.05 ），差异有统计学意义。结论 血清BNP 、 cTnI 及心肌酶谱水平检测在心力衰竭患者中的应用价值较高，可以有效反映心衰的具体情况。 【关键词】 BNP ；cTnI ；心肌酶；心力衰竭；应用价值 【中图分类号】R541.6 【文献标识码】A 【文章编号】 1003—6350(2013)01—0056—03 Application value of the detection of serum BNP, cTnI, myocardial enzymes in patients with heart failure.YUE Yan-jun,DONGCun-yuan,CHENSu-juan.DepartmentofClinicalLaboratory,theThirdAffiliatedHospitalofHebei NorthUniversity,Zhangjiakou075000,Hebei,CHINA 【Abstract 】 Objective To study the application value of the detection of brain natriuretic peptide (BNP), Car- diac Troponin I (cTnI) and myocardial enzyme in patients with heart failure. Methods Fifty-eight patients with heart failure in our hospital from August 2010 to April 2012 were selected as observation group, and 58 healthy individuals undergoing physical examination at the same time were selected as control group. Then the serum BNP, cTnI and myo- cardial enzyme were detected and compared between the two groups. Results The levels of serum BNP, cTnI and myocardial enzyme were all significantly higher in the observation group than the control group, in patients with high- er NYHA grade than patients with lower NYHA gra