生物mond方程（生物mond方程）.doc

生物mond方程（生物mond方程） Cell growth can be divided into five stages: hysteresis, logarithm, deceleration, stationary and decline. Among them, the main growth period of bacteria is logarithmic: - type in for the specific growth rate, the per unit time per unit cell biomass, when the substrate concentration of S decreased to a certain value, the value is decreased, which is in the deceleration period; with the substrate concentration continued to decline, the cell senescence gradually with the growth balance and more growth, namely access to static and the recession period. J. Monod proposed an empirical relation between mu and S in 1949. This formula is called Monod equation: In the formula, M is the maximum specific growth rate, that is, the maximum value is not changed by the change of the substrate concentration; Ks is the saturation constant, that is, the quantity is equivalent to the S value of =0.5 mu m. The smaller the Ks value is, the lower the concentration of M is, the more sensitive the S is to the mu, and the lower the critical S value of keeping mu. In general, when S 10Ks, u = s when S? Ks, u = (s/Ks). The formation of products is often related to the growth or concentration of bacteria: The alpha and beta in the formula are constant; the rate of formation of the ratio product. A common formula is used between restriction matrix depletion and cell growth: Where YG is the cell yield constant; 1/YG is only used for base quality synthesis consumed per cell; M cell, which maintain the coefficient of friction for mass per unit time was to maintain life activities; QS consumption rate ratio restriction matrix. If the growth of the cell is accompanied by the formation of the product, YP is the product yield coefficient in the formula, and 1/YP is the base mass used solely for the synthesis of the unit product. Enzyme kinetics The enzymatic reaction rate, the rate of enzyme reaction and the factors affecting the rate of enzyme reaction were studied. It can provide