神经干细胞优势（Advantages of neural stem cells）.docVIP

神经干细胞优势（Advantages of neural stem cells） Stem cells have unique therapeutic advantages because they are homologous to the cells in the spinal cord injury area. Spinal cord injury is a serious hazard to human health disease, injury in patients below the level of injury exists, sensory and motor reflex and urinary dysfunction, the treatment of spinal cord injury research mainly concentrated in the following aspects: the progression of secondary damage control surgery, including reducing pressure, hormone impact therapy, mild hypothermia, calcium channel blocking excitatory amino acid antagonists, and free radical scavenging. Promoting axonal regeneration, repairing damaged myelin sheath, enhancing plasticity of central nervous system and promoting compensatory function in non damaged areas, including cell transplantation and nerve growth factor. 3. Various factors that inhibit axonal regeneration after or after spinal cord injury, including the use of anti axonal growth inhibitory factors, gene silencing and other techniques, indirectly promote axonal regeneration. The research of transplantation vectors mainly focuses on embryonic spinal cord tissue, neural stem cells, peripheral nerves, Schwann cells and genetically modified functional cells. It has been proved that the transplantation of these vectors can help the recovery of the nervous system. Stem cells have unique therapeutic advantages because they are homologous with those in the spinal cord injury area. After spinal cord injury, the blood spinal cord barrier is destroyed, ischemia and hypoxia, and a variety of inflammatory factors into the injury area, triggering the combined effect of necrosis and apoptosis. While the remaining nerve cells are damaged, it also damages the spinal cord tissue at the edge of the spinal cord. Therefore, the prevention of secondary injury is an important part of early treatment. From the point of view of pathophysiological mechanism, the change of local microenvironment after sp