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about diclofenac induced edema 1 cases(双氯芬酸引起的水肿1例)
About diclofenac induced edema 1 cases
[Keywords] double Dove sodium, edema 1 Clinical data Patients, female, 56 years old, due to repeated migratory shoulder, limbs, arthralgia January heavier and hands knuckle pain three days of treatment admission, no history of hypertensive heart disease. Examination systemic generally good, major joint activities freely, hands food, and little finger joints slight swelling, high local temperature, fist slightly limited blood as normal, anti-”O” lt;200 U / L, erythrocyte sedimentation rate 24 mm / h, CRP 24 mg / L, RF-negative, liver and normal renal function, bone density examination: bone density reduce osteoporosis diagnosis: the ① allergic arthritis, the ② degenerative arthritis. give Limaixian 0.25 g, 1 times / d, diclofenac (Dick Luck 75 mg, 1 times / d, 2 Osteoform calcium, 1 / d, Alpha D3 capsules 25 g, 1 times / d, orally, for 4 d significantly alleviate joint pain normal finger joints fist, but feel the whole body swelling sense and gradually increased, eyelids, lower limbs obvious increase in 1 wk body quality of 0.25 kg review: erythrocyte sedimentation rate 16 mm / h, CRP 14 mg / L, liver and kidney function electrolytes normal, disable diclofenac, clothing hydrochlorothiazide grams urine plug 25 mg, 1 times / d, furosemide 20 mg, 1 times / d, 5 d after the edema improved body weight returned to normal.
2 Discussion Diclofenac generic name, Dick Luck trade name is a non-steroidal anti-inflammatory drugs and COX nonspecific inhibitors, drug side effects and indole indomethacin, topiramate Hello meloxicam significantly reduced [1]. Commonly used in various kinds of inflammatory arthritis, gouty arthritis, soft tissue rheumatism, its main adverse gastrointestinal reactions, unusual headaches, dizziness, increased liver enzymes GOT decreased renal function, sodium and water retention, edema patients hypertension, a history of heart disease, but getting medication after 4 d anasarca, weight gain, plus diu
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